Role of Agents other than Tumor Necrosis Factor Blockers in the Treatment of Psoriatic Arthritis

被引：9

作者：

Atzeni, Fabiola ^{[1
]}

Costa, Luisa ^{[2
,3
]}

Caso, Francesco ^{[2
]}

Scarpa, Raffaele ^{[2
]}

Sarzi-Puttini, Piercarlo ^{[2
]}

机构：

[1] IRCCS Galeazzi Orthoped Inst, I-20161 Milan, Italy

[2] Univ Naples Federico II, Dept Clin Med & Surg, Rheumatol Res Unit, Naples, Italy

[3] Univ Padua, DIMED, Dept Clin Med, Rheumatol Unit, Padua, Italy

来源：

JOURNAL OF RHEUMATOLOGY | 2015年 / 42卷

关键词：

PSORIATIC ARTHRITIS; TUMOR NECROSIS FACTOR INHIBITORS; APREMILAST; USTEKINUMAB; INTERLEUKIN-17; INHIBITORS; RITUXIMAB; TOCILIZUMAB; RECOMMENDATIONS; USTEKINUMAB; MANAGEMENT; PATIENT; DISEASE;

D O I：

10.3899/jrheum.150643

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

Psoriatic arthritis (PsA) is a systemic inflammatory disease characterized by possible peripheral and axial joint involvement, enthesitis, dactylitis, and skin and nail disease. It affects up to one-third of psoriatic patients, and may be associated with comorbidities such as cardiovascular and metabolic diseases. The usually prescribed initial treatment of moderate-severe PsA is methotrexate, which may be accompanied or replaced by a tumor necrosis factor (TNF) inhibitor such as etanercept, infliximab, or adalimumab. However, some patients may become unresponsive (or have contraindications) to available anti-TNF agents and require alternative treatment. The aim of this review is to describe the potential role of some new immunomodulatory agents.

引用

收藏

页码：79 / 81

页数：3

相关论文

共 21 条

[1]

Interleukin 6 Blockade: Tocilizumab in Psoriatic Arthritis [J].

Atzeni, Fabiola ;

Ventura, Donatella ;

Batticciotto, Alberto ;

Boccassini, Laura ;

Sarzi-Puttini, Piercarlo .

JOURNAL OF RHEUMATOLOGY, 2012, 39 :97-99

[2]

Resistant Cases of Psoriatic Arthritis: How to Manage Them [J].

Atzeni, Fabiola ;

Sarzi-Puttini, Piercarlo ;

Vena, Gino Antonio .

JOURNAL OF RHEUMATOLOGY, 2009, 36 :73-75

[3]

Refractory pemphigus foliaceus and Beh‡et's disease successfully treated with tocilizumab [J].

Caso, Francesco ;

Iaccarino, Luca ;

Bettio, Silvano ;

Ometto, Francesca ;

Costa, Luisa ;

Punzi, Leonardo ;

Doria, Andrea .

IMMUNOLOGIC RESEARCH, 2013, 56 (2-3) :390-397

[4]

Geoepidemiology and environmental factors of psoriasis and psoriatic arthritis [J].

Chandran, Vinod ;

Raychaudhuri, Siba P. .

JOURNAL OF AUTOIMMUNITY, 2010, 34 (03) :J314-J321

[5]

Successful treatment of psoriatic arthritis with rituximab [J].

Cohen, J. D. .

ANNALS OF THE RHEUMATIC DISEASES, 2008, 67 (11) :1647-1648

[6]

Efficacy of tocilizumab in a patient with refractory psoriatic arthritis [J].

Costa, Luisa ;

Caso, Francesco ;

Cantarini, Luca ;

Del Puente, Antonio ;

Scarpa, Raffaele ;

Atteno, Mariangela .

CLINICAL RHEUMATOLOGY, 2014, 33 (09) :1355-1357

[7]

Psoriatic arthritis is associated with increased arterial stiffness in the absence of known cardiovascular risk factors: a case control study [J].

Costa, Luisa ;

Caso, Francesco ;

D'Elia, Lanfranco ;

Atteno, Mariangela ;

Peluso, Rosario ;

Del Puente, Antonio ;

Strazzullo, Pasquale ;

Scarpa, Raffaele .

CLINICAL RHEUMATOLOGY, 2012, 31 (04) :711-715

[8]

Tocilizumab in Adult-onset Still's Disease: the Israeli Experience [J].

Elkayam, Ori ;

Jiries, Nizar ;

Dranitzki, Zvi ;

Kivity, Shay ;

Lidar, Merav ;

Levy, Ofer ;

Ablin, Jacob ;

Abu-Shakra, Mahmoud ;

Savargyl-Maman, Hagit ;

Padova, Hagit ;

Caspi, Dan ;

Rosner, Itzhak .

JOURNAL OF RHEUMATOLOGY, 2014, 41 (02) :244-247

[9]

JAK/STAT/PKCδ molecular pathways in synovial fluid T lymphocytes reflect the in vivo T helper-17 expansion in psoriatic arthritis [J].

Fiocco, Ugo ;

Accordi, Benedetta ;

Martini, Veronica ;

Oliviero, Francesca ;

Facco, Monica ;

Cabrelle, Anna ;

Piva, Lucia ;

Molena, Beatrice ;

Caso, Francesco ;

Costa, Luisa ;

Scanu, Anna ;

Pagnin, Elisa ;

Atteno, Mariangela ;

Scarpa, Raffaele ;

Basso, Giuseppe ;

Semenzato, Gianpietro ;

Punzi, Leonardo ;

Doria, Andrea ;

Dayer, Jean-Michel .

IMMUNOLOGIC RESEARCH, 2014, 58 (01) :61-69

[10]

European League Against Rheumatism recommendations for the management of psoriatic arthritis with pharmacological therapies [J].

Gossec, L. ;

Smolen, J. S. ;

Gaujoux-Viala, C. ;

Ash, Z. ;

Marzo-Ortega, H. ;

van der Heijde, D. ;

FitzGerald, O. ;

Aletaha, D. ;

Balint, P. ;

Boumpas, D. ;

Braun, J. ;

Breedveld, F. C. ;

Burmester, G. ;

Canete, J. D. ;

de Wit, M. ;

Dagfinrud, H. ;

de Vlam, K. ;

Dougados, M. ;

Helliwell, P. ;

Kavanaugh, A. ;

Kvien, T. K. ;

Landewe, R. ;

Luger, T. ;

Maccarone, M. ;

McGonagle, D. ;

McHugh, N. ;

McInnes, I. B. ;

Ritchlin, C. ;

Sieper, J. ;

Tak, P. P. ;

Valesini, G. ;

Vencovsky, J. ;

Winthrop, K. L. ;

Zink, A. ;

Emery, P. .

ANNALS OF THE RHEUMATIC DISEASES, 2012, 71 (01) :4-12