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Population genetic models of duplicated genes

被引：57
作者：
Innan, Hideki [1 ]
机构：
[1] Grad Univ Adv Studies, Kanagawa 2400193, Japan
来源：
GENETICA | 2009年 / 137卷 / 01期
基金：
日本学术振兴会;
关键词：
Gene duplication; Population genetics; Selection; Mutation; Adaptive evolution; Theory; HISTOCOMPATIBILITY COMPLEX LOCI; COPY-NUMBER VARIATION; CONCERTED EVOLUTION; MULTIGENE FAMILIES; FINITE POPULATION; HUMAN GENOME; SACCHAROMYCES-CEREVISIAE; DROSOPHILA-MELANOGASTER; DIVERSIFYING SELECTION; STATISTICAL TESTS;
D O I：
10.1007/s10709-009-9355-1
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
Various population genetic models of duplicated genes are introduced. The problems covered in this review include the fixation process of a duplicated copy, copy number polymorphism, the fates of duplicated genes and single nucleotide polymorphism in duplicated genes. Because of increasing evidence for concerted evolution by gene conversion, this review introduces recently developed gene conversion models. In the first half, models assuming independent evolution of duplicated genes are introduced, and then the effect of gene conversion is considered in the second half.
引用
收藏
页码：19 / 37
页数：19
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