High headache prevalence among women with hemochromatosis:: The Nord-Trondelag Health Study

被引：21

作者：

Hagen, K ^{[1
]}

Stovner, LJ

Åsberg, A

Thorstensen, K

Bjerve, KS

Hveem, K

机构：

[1] Norwegian Univ Sci & Technol, Fac Med, Dept Clin Neurosci, Neurol Sect, N-7006 Trondheim, Norway

[2] Univ Trondheim Hosp, Dept Clin Chem, Trondheim, Norway

[3] Innherred Hosp, Levanger, Norway

来源：

ANNALS OF NEUROLOGY | 2002年 / 51卷 / 06期

关键词：

D O I：

10.1002/ana.10209

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

In this large cross-sectional population-based study, 51,272 persons responded to a headache questionnaire and were screened for hemochromatosis. Phenotypic hemochromatosis and the C282Y/C282Y genotype were both associated with an 80% increase in headache prevalence evident only among women. The reason for this association is unclear, but one may speculate that iron overload alters the threshold for triggering a headache by disturbing neuronal function.

引用

页码：786 / 789

页数：4

共 11 条

[1]

Åsberg A, 2001, SCAND J GASTROENTERO, V36, P1108

[2] FERRITIN, TRANSFERRIN, AND IRON IN SELECTED REGIONS OF THE ADULT AND AGED RAT-BRAIN [J].