A profile of candidates for repeat myocardial revascularization: Implications for selection of treatment

被引:13
作者
Brener, SJ
Loop, FD
Lytle, BW
Ellis, SG
Cosgrove, DM
Topol, EJ
机构
[1] CLEVELAND CLIN FDN, DEPT CARDIOL, CLEVELAND, OH 44195 USA
[2] CLEVELAND CLIN FDN, DEPT THORAC & CARDIOVASC SURG, CLEVELAND, OH 44195 USA
关键词
D O I
10.1016/S0022-5223(97)70139-9
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objectives: It is not known whether the results of randomized trials comparing coronary artery bypass grafting to percutaneous transluminal coronary angioplasty for initial revascularization apply to repeat revascularization in patients with prior bypass grafts. We studied the differences between the patients with prior bypass grafts referred for surgery or angioplasty to identify the clinical and angiographic characteristics that correlated best with either choice and to find clues that might aid in selecting one treatment over the other. Methods: Between 1992 and 1904, 870 patients underwent first isolated reoperation and 793 patients underwent first balloon angioplasty after a previous operation. A jeopardy score (0 to 8 points) was derived for each patient on the basis of the relative size of the ischemic territory. Clinical and angiographic data were analyzed for association with the revascularization strategy, Results: The following characteristics were more prevalent in the reoperation group: male sex, diabetes, hypertension, valvular disease, normocholesterolemia, and severe left ventricular systolic dysfunction; fewer functioning venous and arterial grafts; and a higher jeopardy score (p < 0.01 for all) than in the angioplasty group. A higher jeopardy score, diabetes, and a lower number of functioning arterial or venous grafts were strong, independent predictors of referral for reoperation (p < 0.01 for all). In-hospital death and Q-wave infarction (p < 0.01 for both) were more frequent in the reoperation group. Conclusions: Reoperation was the revascularization procedure of choice when larger regions of myocardium were in jeopardy, Angioplasty was more frequently chosen in the presence of a patent arterial graft to the left anterior descending coronary artery or multiple functioning bypass grafts. Reoperation was associated with a higher risk of in-hospital complications than angioplasty.
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页码:153 / 161
页数:9
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