Three new sesquiterpenes from the black heartwood of Cryptomeria japonica

被引:16
作者
Arihara, S [1 ]
Umeyama, A [1 ]
Bando, S [1 ]
Imoto, S [1 ]
Ono, M [1 ]
Yoshikawa, K [1 ]
机构
[1] Tokushima Bunri Univ, Fac Pharmaceut Sci, Tokushima 7708514, Japan
关键词
Cryptomeria japonicaca; Taxodiaceae; black heartwood; sesquiterpenoid; antibacterial activity; termiticidal activity;
D O I
10.1248/cpb.52.463
中图分类号
R914 [药物化学];
学科分类号
100701 [药物化学];
摘要
Three new sesquiterpenes, (4S)-2,6,10-bisaboratrien-4-ol-1-one (1), 1,8-epoxy-1(6),2,4,7,10-bisaborapentaen-4-ol (2), and 1-methoxy-4-cadinene (3) have been isolated from the black heartwood of Ctyptomeria japonica. Compounds 1 and 2 were designated sugikurojinols A and B, respectively, and the structures of compounds 1-3 were established by extensive NMR experiments. Compounds 1 and 2 were also examined for antibacterial activity against Staphylococcus aureus and Escherichia coli, and for termiticidal activity against Coptotermes formosanus SHIRAKI.
引用
收藏
页码:463 / 465
页数:3
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