Ceramic processing of beta-TCP for producing implantable shapes.

被引:6
作者
Franco, J.
Souto, A.
Rey, P.
Guitian, F.
Martinez Insua, A.
机构
[1] Inst Ceram Galicia, Santiago De Compostela 15706, Spain
[2] Univ Santiago de Compostela, Fac Med & Odontol, Santiago De Compostela 15782, Spain
来源
BOLETIN DE LA SOCIEDAD ESPANOLA DE CERAMICA Y VIDRIO | 2006年 / 45卷 / 04期
关键词
beta-TCP; synthesis; gelcasting; LPIM;
D O I
10.3989/cyv.2006.v45.i4.283
中图分类号
TQ174 [陶瓷工业]; TB3 [工程材料学];
学科分类号
0805 [材料科学与工程]; 080502 [材料学];
摘要
This work describes a method for obtaining large-scale productions of beta-TCP by mass-precipitation from calcium and phosphate solutions. The setting of the synthesis conditions was made by studying operational parameters like the concentrations of the reagents, the speed of the mixing of the reagents, pH of precipitation and ageing of the precipitate. This synthesis procedure allows obtaining high purity P-TCP under ASTM F1088-87. Starting from synthesized P-TCP were made rods for implantation by die pressing, slip casting, gel casting and low pressure injection moulding. These rods were well characterized and implanted in Beagle dogs. Thin film histological results for 2, 7, and 14 months of implantation period, shown a good biocompatibility for the material and its resorbable behaviour.
引用
收藏
页码:265 / 270
页数:6
相关论文
共 20 条
[2]
[Anonymous], 2004, EUR J TRAUMA EMERG S
[3]
Porous titanium-nickel for intervertebral fusion in a sheep model: Part 1. Histomorphometric and radiological analysis [J].
Assad, M ;
Jarzem, P ;
Leroux, MA ;
Coillard, C ;
Chernyshov, AV ;
Charette, S ;
Rivard, CH .
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS, 2003, 64B (02) :107-120
[4]
CHOW L, 1983, Patent No. 4518430
[5]
SKELETAL REPAIR BY IN-SITU FORMATION OF THE MINERAL PHASE OF BONE [J].
CONSTANTZ, BR ;
ISON, IC ;
FULMER, MT ;
POSER, RD ;
SMITH, ST ;
VANWAGONER, M ;
ROSS, J ;
GOLDSTEIN, SA ;
JUPITER, JB ;
ROSENTHAL, DI .
SCIENCE, 1995, 267 (5205) :1796-1799
[6]
Biphasic calcium phosphate concept applied to artificial bone, implant coating and injectable bone substitute [J].
Daculsi, G .
BIOMATERIALS, 1998, 19 (16) :1473-1478
[7]
CRYSTAL DISSOLUTION OF BIOLOGICAL AND CERAMIC APATITES [J].
DACULSI, G ;
LEGEROS, RZ ;
MITRE, D .
CALCIFIED TISSUE INTERNATIONAL, 1989, 45 (02) :95-103
[8]
DRIESSENS FCM, 1990, FORMATION STABILITY
[9]
GUITIAN F, 1990, BOL SOC ESP CERAM V, V29, P253
[10]
Hench LL, 1998, J AM CERAM SOC, V81, P1705