Advances in the treatment of graft-versus-host disease

被引:9
作者
Vogelsang, GB [1 ]
机构
[1] Johns Hopkins Univ, Baltimore, MD 21287 USA
关键词
GVHD; conditioning; treatment;
D O I
10.1038/sj.leu.2401687
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Graft-versus-host disease (GVHD) is a complicated disease whose treatment requires an equally multifaceted approach. Recipient conditioning, donor T cell activation, and end stage effecters all may be potential targets for treatment. Many drugs used in the past are returning to the forefront for investigation. Some of the newer nucleoside analogs that are in various stages of development, such as fludarabine and pentostatin, are showing promising activity in GVHD.
引用
收藏
页码:509 / 510
页数:2
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