Apheresis therapy for prolonged red cell aplasia after major ABO-mismatched bone marrow transplantation

被引：21

作者：

Ohta, S

Yokoyama, H

Ise, T

Takasawa, K

Wada, T

Nakao, S

Matsuda, T

Kobayashi, K

机构：

[1] Division of Blood Purification, Kanazawa University, Kanazawa

[2] First Dept. of Internal Medicine, Kanazawa University, Kanazawa

[3] Third Dept. of Internal Medicine, Kanazawa University, Kanazawa

[4] Division of Blood Purification, 1st Department of Internal Medicine, Kanazawa University, Ishikawa 920

来源：

INTERNAL MEDICINE | 1997年 / 36卷 / 07期

关键词：

delayed red blood cell (RBC) recovery; double filtration plasma pheresis (DFPP); immunoadsorption;

D O I：

10.2169/internalmedicine.36.487

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Two cases of leukemia were treated successfully with apheresis for delayed recovery of erythropoiesis due to antibody-mediated red cell aplasia after ABO-mismatched bone marrow transplantation (BMT). A 25-year-old female (ABO group O) underwent BMT from her brother (group A), Immunoadsorption using Biosynsorb A performed on day 146 after BMT followed by double filtration plasma pheresis (DFPP) reduced anti-A antibody titers from 1:32 to 1:2. Anemia improved dramatically within 2 weeks. A 49-year-old female (group O) underwent BMT from her mother (group A), She was treated with DFPP on day 131 after BMT, Anti-A antibody titers dropped from 1:16 to 1:1 and anemia improved gradually.

引用

页码：487 / 491

页数：5

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