Response of leptomeningeal metastases from breast cancer to hormonal therapy

被引：57

作者：

Boogerd, W

Dorresteijn, LDA

van der Sande, JJ

de Gast, GC

Bruning, PF

机构：

[1] Netherlands Canc Inst, Dept Neurooncol, Antoni Van Leeuwenhoek Hosp, NL-1066 CX Amsterdam, Netherlands

[2] Netherlands Canc Inst, Dept Med Oncol, Antoni Van Leeuwenhoek Hosp, NL-1066 CX Amsterdam, Netherlands

来源：

NEUROLOGY | 2000年 / 55卷 / 01期

关键词：

D O I：

10.1212/WNL.55.1.117

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Intraventricular chemotherapy with radiotherapy is the standard treatment of leptomeningeal metastasis (LM) from breast cancer; this treatment increases median survival only to about 3 months and is frequently complicated by serious side effects. The authors describe two patients with LM from breast cancer who were treated with hormonal therapy, which provided a neurologic response of at least 12 months and a survival of 14+ and 19 months. Hormonal therapy can be effective and nontoxic for patients with LM from breast cancer.

引用

页码：117 / 119

页数：3

共 14 条

[1]

Bokstein F, 1998, CANCER, V82, P1756, DOI 10.1002/(SICI)1097-0142(19980501)82:9<1764::AID-CNCR24>3.0.CO

[2]

2-1

[3]

BOOGERD W, 1991, CANCER, V67, P1685, DOI 10.1002/1097-0142(19910315)67:6<1685::AID-CNCR2820670635>3.0.CO

[4]

2-M