Exomic Sequencing Identifies PALB2 as a Pancreatic Cancer Susceptibility Gene

被引：574

作者：

Jones, Sian ^{[1
,2
,3
]}

Hruban, Ralph H. ^{[1
,4
]}

Kamiyama, Mihoko ^{[4
]}

Borges, Michael ^{[4
]}

Zhang, Xiaosong ^{[1
,2
,3
]}

Parsons, D. Williams ^{[1
,2
,3
]}

Lin, Jimmy Cheng-Ho ^{[1
,2
,3
]}

Palmisano, Emily ^{[1
]}

Brune, Kieran ^{[1
]}

Jaffee, Elizabeth M. ^{[1
,4
]}

Iacobuzio-Donahue, Christine A. ^{[1
,4
]}

Maitra, Anirban ^{[1
,4
]}

Parmigiani, Giovanni ^{[1
,4
]}

Kern, Scott E. ^{[1
,4
]}

Velculescu, Victor E. ^{[2
,3
]}

Kinzler, Kenneth W. ^{[2
,3
]}

Vogelstein, Bert ^{[1
,2
,3
]}

Eshleman, James R. ^{[1
,4
]}

Goggins, Michael ^{[1
,4
,5
]}

Klein, Alison P. ^{[1
,4
]}

机构：

[1] Johns Hopkins Med Inst, Sol Goldman Pancreat Canc Res Ctr, Dept Oncol, Baltimore, MD 21231 USA

[2] Howard Hughes Med Inst, Baltimore, MD 21231 USA

[3] Ludwig Ctr Canc Genet & Therapeut, Baltimore, MD 21231 USA

[4] Johns Hopkins Med Inst, Sol Goldman Pancreat Canc Res Ctr, Dept Pathol, Baltimore, MD 21231 USA

[5] Johns Hopkins Med Inst, Sol Goldman Pancreat Canc Res Ctr, Dept Med, Baltimore, MD 21231 USA

来源：

SCIENCE | 2009年 / 324卷 / 5924期

关键词：

BREAST-CANCER; FUTURE;

D O I：

10.1126/science.1171202

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

[No abstract available]

引用

页码：217 / 217

页数：1

共 9 条

[1] Core signaling pathways in human pancreatic cancers revealed by global genomic analyses
Jones, Sian
Zhang, Xiaosong
Parsons, D. Williams
Lin, Jimmy Cheng-Ho
Leary, Rebecca J.
Angenendt, Philipp
Mankoo, Parminder
Carter, Hannah
Kamiyama, Hirohiko
Jimeno, Antonio
Hong, Seung-Mo
Fu, Baojin
Lin, Ming-Tseh
Calhoun, Eric S.
Kamiyama, Mihoko
Walter, Kimberly
Nikolskaya, Tatiana
Nikolsky, Yuri
Hartigan, James
Smith, Douglas R.
Hidalgo, Manuel
Leach, Steven D.
Klein, Alison P.
Jaffee, Elizabeth M.
Goggins, Michael
Maitra, Anirban
Iacobuzio-Donahue, Christine
Eshleman, James R.
Kern, Scott E.
Hruban, Ralph H.
Karchin, Rachel
Papadopoulos, Nickolas
Parmigiani, Giovanni
Vogelstein, Bert
Velculescu, Victor E.
Kinzler, Kenneth W.
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[2] *LUSTG FDN PANCR C, CA62924 NIH LUSTG FD
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