Cancer - A bull's eye for targeted lung cancer therapy

被引:59
作者
Minna, JD [1 ]
Gazdar, AF
Sprang, SR
Herz, J
机构
[1] Univ Texas, SW Med Ctr, Dept Internal Med, Dallas, TX 75390 USA
[2] Univ Texas, SW Med Ctr, Dept Pharmacol, Dallas, TX 75390 USA
[3] Univ Texas, SW Med Ctr, Dept Pathol, Hamon Ctr Therapeut Oncol Res, Dallas, TX 75390 USA
[4] Univ Texas, SW Med Ctr, Howard Hughes Med Inst, Dept Biochem, Dallas, TX 75390 USA
[5] Univ Texas, SW Med Ctr, Dept Mol Genet, Dallas, TX 75390 USA
关键词
D O I
10.1126/science.1099578
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
[No abstract available]
引用
收藏
页码:1458 / +
页数:3
相关论文
共 6 条
[1]   The role of EGFR inhibitors in nonsmall cell lung cancer [J].
Ciardiello, F ;
De Vita, F ;
Orditura, M ;
Tortora, G .
CURRENT OPINION IN ONCOLOGY, 2004, 16 (02) :130-135
[2]   ST1571 (Gleevec™) as a paradigm for cancer therapy [J].
Druker, BJ .
TRENDS IN MOLECULAR MEDICINE, 2002, 8 (04) :S14-S18
[3]  
Frederick L, 2000, CANCER RES, V60, P1383
[4]   Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib [J].
Lynch, TJ ;
Bell, DW ;
Sordella, R ;
Gurubhagavatula, S ;
Okimoto, RA ;
Brannigan, BW ;
Harris, PL ;
Haserlat, SM ;
Supko, JG ;
Haluska, FG ;
Louis, DN ;
Christiani, DC ;
Settleman, J ;
Haber, DA .
NEW ENGLAND JOURNAL OF MEDICINE, 2004, 350 (21) :2129-2139
[5]   EGFR mutations in lung cancer:: Correlation with clinical response to gefitinib therapy [J].
Paez, JG ;
Jänne, PA ;
Lee, JC ;
Tracy, S ;
Greulich, H ;
Gabriel, S ;
Herman, P ;
Kaye, FJ ;
Lindeman, N ;
Boggon, TJ ;
Naoki, K ;
Sasaki, H ;
Fujii, Y ;
Eck, MJ ;
Sellers, WR ;
Johnson, BE ;
Meyerson, M .
SCIENCE, 2004, 304 (5676) :1497-1500
[6]   Lung cancer in US women - A contemporary epidemic [J].
Patel, JD ;
Bach, PB ;
Kris, MG .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2004, 291 (14) :1763-1768