The immunogenetics of autoimmune diabetes and autoimmune thyroid disease

被引:25
作者
Tomer, Y [1 ]
Barbesino, G [1 ]
Greenberg, D [1 ]
Davies, TF [1 ]
机构
[1] CUNY MT SINAI SCH MED, DEPT PSYCHIAT, NEW YORK, NY 10029 USA
关键词
D O I
10.1016/S1043-2760(96)00266-4
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Although medical genetics is a well-developed area of interest, relatively little is known about the diseases caused by the combination of many genes. These multiinfluenced diseases include the autoimmune endocrine diseases. Recent advances in the techniques for whole-genome screening have shown a variety of loci that are linked to the development of insulin-dependent diabetes mellitus, and similar data are likely to be soon generated in autoimmune thyroid disease. Here, the authors survey the current state of genetic knowledge in these two areas and describe the investigative and analytical techniques that are now available. (C) 1997, Elsevier Science Inc.
引用
收藏
页码:63 / 70
页数:8
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