Morbidity in Pediatric Burns, Toxic Shock Syndrome, and Antibiotic Prophylaxis A Retrospective Comparative Study

被引:10
作者
Mulgrew, Stephen [1 ]
Khoo, Anna [2 ]
Cartwright, Rufus [3 ,4 ]
Reynolds, Nick [5 ]
机构
[1] Lister Hosp, Dept Plast Surg, Stevenage, Herts, England
[2] Addenbrookes Hosp, Dept Plast Surg, Cambridge, England
[3] Univ London Imperial Coll Sci Technol & Med, Dept Urogynaecol, London, England
[4] Univ London Imperial Coll Sci Technol & Med, Dept Epidemiol & Biostat, London, England
[5] Salisbury Hosp Odstock, Dept Plast Surg, Salisbury, Wilts, England
基金
英国医学研究理事会;
关键词
toxic shock syndrome; burns; sepsis; pediatric; antibiotic prophylaxis; STAPHYLOCOCCAL TOXEMIA; EARLY-DIAGNOSIS; CHILDREN; PREVENTION; FEVER;
D O I
10.1097/SAP.0b013e31829be8be
中图分类号
R61 [外科手术学];
学科分类号
100210 [外科学];
摘要
The prophylactic use of antibiotic for pediatric burns has been suggested as a possible means of reduction of toxic shock syndrome. In our study, we review 1250 burn cases during a 16-year period (1983-1999). There was a change in protocol during this period (after 1991, all pediatric burn received prophylactic antibiotics irrespective of presentation), thus creating 2 groups: our control who received antibiotics when clinically necessary and our cases who received antibiotics as routine prophylaxis. Our results show no statistical difference between the 2 groups both in signs of morbidity and signs of potential toxic shock syndrome. We conclude that prophylactic antibiotic use is unnecessary and the use of antibiotics should be guided on a case by case basis according to symptoms.
引用
收藏
页码:34 / 37
页数:4
相关论文
共 22 条
[1]
National variations in dressings and antibiotic prophylaxis for paediatric scalds [J].
Al-Benna, Sammy ;
Collin, Thomas W. ;
Spalding, Lynette ;
Jeffery, Steven .
BURNS, 2007, 33 (06) :798-799
[2]
Recurrent nonmenstrual toxic shock syndrome: Clinical manifestations, diagnosis, and treatment [J].
Andrews, MM ;
Parent, EM ;
Barry, M ;
Parsonnet, J .
CLINICAL INFECTIOUS DISEASES, 2001, 32 (10) :1470-1479
[3]
Bacterial toxicosis/toxic shock syndrome as a contributor to morbidity in children with burn injuries [J].
Brown, AP ;
Khan, K ;
Sinclair, S .
BURNS, 2003, 29 (07) :733-738
[4]
Toxic shock syndrome in paediatric burns: A peculiarly British malady or a malady of peculiar British? [J].
Burd, A .
BURNS, 2005, 31 (07) :937-938
[5]
FEVER IN BURNED CHILDREN [J].
CHILDS, C .
BURNS, 1988, 14 (01) :1-6
[6]
The acute febrile response to burn injury in children may be modified by the type of intravenous fluid used during resuscitation - observations using fresh frozen plasma (FFP) or Hartmann's solution [J].
Childs, C ;
Renshaw, A ;
Dunn, KW ;
Davenport, PJ .
BURNS, 2001, 27 (04) :386-388
[7]
TOXIC SHOCK SYNDROME IN SCALDED CHILDREN [J].
COLE, RP ;
SHAKESPEARE, PG .
BURNS, 1990, 16 (03) :221-224
[8]
IMPACT ON COST OF INAPPROPRIATE INITIAL EMPIRICAL USE OF ANTIBIOTIC IN PATIENTS WITH COMPLICATED INFECTIONS FROM TWO LARGE BRAZILIAN HOSPITALS [J].
Cyrillo, M. ;
Araujo, G. T. B. ;
Aldrighi, D. ;
Fonseca, M. ;
Monteiro, R. ;
Etto, H. .
VALUE IN HEALTH, 2010, 13 (03) :A188-A188
[9]
DESAXE MJ, 1985, POSTGRAD MED J, V61, P5
[10]
A survey into toxic shock syndrome (TSS) in UK burns units [J].
Edwards-Jones, V ;
Dawson, MM ;
Childs, C .
BURNS, 2000, 26 (04) :323-333