Synthesis of key intermediates for a concise and convergent approach to the marine natural product eleutherobin

被引：29

作者：

Baron, A ^{[1
]}

Caprio, V ^{[1
]}

Mann, J ^{[1
]}

机构：

[1] Univ Reading, Dept Chem, Reading RG6 6AD, Berks, England

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 52期

关键词：

D O I：

10.1016/S0040-4039(99)01956-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Synthesis of 1,6-syn-5,6-anti-2-methyl-5-isopropyl-bicyclo[4.3.0]non-2-en-8-one in three steps from (rac)-phellandrene; and 1,6-syn-1-methyl-6-methoxy-3-aza-9-oxabicyclo[4.2.1]non-7-en-4-one in five steps from 2-methoxy-5-methylfuran and tetrabromoacetone, provided these key intermediates for the construction of the skeleton of eleutherobin. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：9321 / 9324

页数：4

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