Functional models for iron-bleomycin

被引：47

作者：

Roelfes, G

Lubben, M

Leppard, SW

Schudde, EP

Hermant, RM

Hage, R

Wilkinson, EC

Que, L

Feringa, BL

机构：

[1] UNIV GRONINGEN,DEPT ORGAN & MOL INORGAN CHEM,NL-9747 AG GRONINGEN,NETHERLANDS

[2] UNILEVER RES LABS VLAARDINGEN,NL-3133 AT VLAARDINGEN,NETHERLANDS

[3] UNIV MINNESOTA,DEPT CHEM,MINNEAPOLIS,MN 55455

来源：

JOURNAL OF MOLECULAR CATALYSIS A-CHEMICAL | 1997年 / 117卷 / 1-3期

关键词：

hydroperoxide compounds; nonheme iron compounds; oxygen activation;

D O I：

10.1016/S1381-1169(96)00356-1

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

A new pentadentate ligand, N, N-bis(2-pyridylmethyl)-N-bis(2-pyridyl)methylamine (N4Py), has been prepared. The corresponding iron(II) complex, [N4PyFe(CH3CN)](ClO4)(2), serves as a functional model for the active site of iron-bleomycin. Upon treatment with H2O2 the formation of a purple intermediate has been observed, which has been characterized as an iron(III)-hydroperoxide complex. This N4Py-iron-hydroperoxide system has proven to be an active oxidation catalyst.

引用

页码：223 / 227

页数：5

共 20 条

[1] THE SELECTIVE FUNCTIONALIZATION OF SATURATED-HYDROCARBONS - GIF CHEMISTRY [J].