The developmental origins of mammalian oocyte polarity

被引：38

作者：

Albertini, DF ^{[1
]}

Barrett, SL

机构：

[1] Tufts Univ, Sch Med, Dept Anat & Cellular Biol, Boston, MA 02111 USA

[2] Marine Biol Lab, Woods Hole, MA 02543 USA

[3] Tufts Univ, Sch Med, Boston, MA 02111 USA

来源：

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY | 2004年 / 15卷 / 05期

关键词：

centrosome; oocyte; transzonal projection; polarity;

D O I：

10.1016/j.semcdb.2004.04.001

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Drosophila has been an excellent model system to study the cell and molecular determinants of oocyte axis specification, a problem which is little known in mammalian species. Recent evidence supports the notion that mammalian oocytes utilize axis-orienting properties during the course of oogenesis. Among these, axis specification in relation to the oocyte cortex, germinal vesicle (GV) position, anchoring of GV and spindle, and patterning of follicle cell/oocyte attachments are proposed as conserved features of oogenesis in mammals that may be important to the survival and development of the preimplantation embryo. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：599 / 606

页数：8

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