Autoimmune mechanisms in the pathophysiology of myelodysplastic syndromes and their clinical relevance

被引:54
作者
Barrett, A. John [1 ]
Sloand, Elaine [1 ]
机构
[1] NHLBI, Hematol Branch, Stem Cell Allotransplantat Sect, NIH, Bethesda, MD 20892 USA
来源
HAEMATOLOGICA-THE HEMATOLOGY JOURNAL | 2009年 / 94卷 / 04期
关键词
SYNDROME MDS; ANTITHYMOCYTE GLOBULIN; CHRONIC INFLAMMATION; ULCERATIVE-COLITIS; CD34; CELLS; PROFILES; THERAPY;
D O I
10.3324/haematol.2009.006080
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:449 / 451
页数:3
相关论文
共 18 条
[1]   Immune mediated autologous cytotoxicity against hematopoietic precursor cells in patients with myelodysplastic syndrome [J].
Chamuleau, Martine E. D. ;
Westers, Theresia M. ;
van Dreunen, Linda ;
Groenland, Judith ;
Zevenbergen, Adri ;
Eeltink, Corien M. ;
Ossenkoppele, Gert J. ;
de Loosdrecht, Arjan A. van .
HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 2009, 94 (04) :496-506
[2]   Distinctive gene expression profiles of CD34 cells from patients with myelodysplastic syndrome characterized by specific chromosomal abnormalities [J].
Chen, GB ;
Zeng, WH ;
Miyazato, A ;
Billings, E ;
Maciejewski, JP ;
Kajigaya, S ;
Sloand, EM ;
Young, NS .
BLOOD, 2004, 104 (13) :4210-4218
[3]   Nitric oxide and p53 in cancer-prone chronic inflammation and oxyradical overload disease [J].
Goodman, JE ;
Hofseth, LJ ;
Hussain, SP ;
Harris, CC .
ENVIRONMENTAL AND MOLECULAR MUTAGENESIS, 2004, 44 (01) :3-9
[4]  
HAMBLIN TJ, 1987, BRIT J HOSP MED, V38, P558
[5]   Loss of T-lymphocyte clonal dominance in patients with myelodysplastic syndrome responsive to immunosuppression [J].
Kochenderfer, JN ;
Kobayashi, S ;
Wieder, ED ;
Su, CL ;
Molldrem, JJ .
BLOOD, 2002, 100 (10) :3639-3645
[6]   CD4+CD25high Foxp3+ regulatory T cells in myelodysplastic syndrome (MDS) [J].
Kordasti, Shahram Y. ;
Ingram, Wendy ;
Hayden, Janet ;
Darling, David ;
Barber, Linda ;
Afzali, Behdad ;
Lombardi, Giovanna ;
Wlodarski, Marcin W. ;
Maciejewski, Jaroslaw P. ;
Farzaneh, Farzin ;
Mufti, Ghulam J. .
BLOOD, 2007, 110 (03) :847-850
[7]   Haematological response of patients with myelodysplastic syndrome to antithymocyte globulin is associated with a loss of lymphocyte-mediated inhibition of CFU-GM and alterations in T-cell receptor Vβ profiles [J].
Molldrem, JJ ;
Jiang, YZ ;
Stetler-Stevenson, M ;
Mavroudis, D ;
Hensel, N ;
Barrett, AJ .
BRITISH JOURNAL OF HAEMATOLOGY, 1998, 102 (05) :1314-1322
[8]  
Mufti Ghulam, 2003, Hematology Am Soc Hematol Educ Program, P176
[9]   Chromosomal instability in ulcerative colitis is related to telomere shortening [J].
O'Sullivan, JN ;
Bronner, MP ;
Brentnall, TA ;
Finley, JC ;
Shen, WT ;
Emerson, S ;
Emond, MJ ;
Gollahon, KA ;
Moskovitz, AH ;
Crispin, DA ;
Potter, JD ;
Rabinovitch, PS .
NATURE GENETICS, 2002, 32 (02) :280-284
[10]   Wilms tumor gene peptide-based immunotherapy for patients with overt leukemia from myelodysplastic syndrome (MDS) or MDS with myelofibrosis [J].
Oka, Y ;
Tsuboi, A ;
Murakami, M ;
Hirai, M ;
Tominaga, N ;
Nakajima, H ;
Elisseeva, OA ;
Masuda, T ;
Nakano, A ;
Kawakami, M ;
Oji, Y ;
Ikegame, K ;
Hosen, N ;
Udaka, K ;
Yasukawa, M ;
Ogawa, H ;
Kawase, L ;
Sugiyama, H .
INTERNATIONAL JOURNAL OF HEMATOLOGY, 2003, 78 (01) :56-61