Neuroendocrine modulation of cancer progression

被引:100
作者
Armaiz-Pena, Guillermo N. [1 ,3 ]
Lutgendorf, Susan K. [4 ,5 ,6 ]
Cole, Steve W. [7 ]
Sood, Anil K. [1 ,2 ]
机构
[1] Univ Texas MD Anderson Canc Ctr, Dept Gynecol Oncol, Houston, TX 77030 USA
[2] Univ Texas MD Anderson Canc Ctr, Dept Canc Biol, Houston, TX 77030 USA
[3] Univ Texas Houston, Hlth Sci Ctr, Grad Sch Biomed Sci, Program Canc Biol, Houston, TX USA
[4] Univ Iowa, Dept Psychol, Iowa City, IA 52242 USA
[5] Univ Iowa, Dept Obstet & Gynecol, Iowa City, IA 52242 USA
[6] Univ Iowa, Dept Urol, Iowa City, IA 52242 USA
[7] Univ Calif Los Angeles, Sch Med, Dept Med, Div Hematol Oncol, Los Angeles, CA 90024 USA
关键词
Cancer; Behavioral stress; Angiogenesis; Metastasis; ENDOTHELIAL GROWTH-FACTOR; BETA-ADRENERGIC-RECEPTORS; OVARIAN-CARCINOMA CELLS; STRESSFUL LIFE EVENTS; BREAST-CANCER; PSYCHOSOCIAL FACTORS; NEUROBLASTOMA-CELLS; TUMOR-GROWTH; SUBSTANCE-P; RISK;
D O I
10.1016/j.bbi.2008.06.007
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Clinical and animal studies now support the notion that psychological factors such as stress, chronic depression, and lack of social support might promote tumor growth and progression. Recently, cellular and molecular studies have started to identify biological processes that could mediate such effects. This review provides a mechanistic understanding of the relationship between biological and behavioral influences in cancer and points to more comprehensive behavioral and pharmacological approaches for better patient outcomes. (c) 2008 Elsevier Inc. All rights reserved.
引用
收藏
页码:10 / 15
页数:6
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