Flipping riboswitches

被引:49
作者
Nudler, Evgeny [1 ]
机构
[1] NYU, Sch Med, Dept Biochem, New York, NY 10016 USA
关键词
D O I
10.1016/j.cell.2006.06.024
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Riboswitches are common cis-acting regulatory elements in bacteria. They are made of nascent RNA that changes its conformation in response to direct binding of cognate metabolites. The publication of five high-resolution crystal structures provides a comprehensive view of how riboswitches sense their ligands and points to new challenges in this emerging field.
引用
收藏
页码:19 / 22
页数:4
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