An assessment of the comparative sensitization potential of some common isothiazolinones

被引：29

作者：

Alexander, BR ^{[1
]}

机构：

[1] Thor Grp Management Ltd, Margate CT9 4JY, Kent, England

来源：

CONTACT DERMATITIS | 2002年 / 46卷 / 04期

关键词：

antimicrobials; benzisothiazolinone; biocides; contact allergy; dichloroisothiazolinone; methylchloroisothiazolinone; methylisothiazolinone; octylisothiazolinone; preservatives;

D O I：

10.1034/j.1600-0536.2002.460402.x

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

The isothiazolinones are known contact sensitizers. Data are presented which demonstrate that, in comparison with the chlorinated and dichlorinated compounds which share immunological cross-reactivity, the unchlorinated isothiazolinones have a lower potential for sensitization and no documented immunological cross-reaction with the chlorinated isothiazolinones.

引用

页码：191 / 196

页数：6

共 20 条

[1]

[Anonymous], 1992, J AM COLL TOXICOL, V11, P75

[2]

BASKETTER D, 2001, EXP DERMATOL, V10, P215

[3] Skin sensitization risk assessment: a comparative evaluation of 3 isothiazolinone biocides [J].

Basketter, DA ;

Rodford, R ;

Kimber, I ;

Smith, I ;

Wahlberg, JE .

CONTACT DERMATITIS, 1999, 40 (03) :150-154

[4] ASSESSMENT OF THE RELATIVE SKIN SENSITIZING POTENCY OF 3-BIOCIDES USING THE MURINE LOCAL LYMPH-NODE ASSAY [J].

BOTHAM, PA ;

HILTON, J ;

EVANS, CD ;

LEES, D ;

HALL, TJ .

CONTACT DERMATITIS, 1991, 25 (03) :172-177

[5]

Bruze M, 1987, Derm Beruf Umwelt, V35, P165

[6] CONTACT ALLERGY TO DICHLORINATED METHYLISOTHIAZOLINONE [J].

BRUZE, M ;

DAHLQUIST, I ;

GRUVBERGER, B .

CONTACT DERMATITIS, 1989, 20 (03) :219-220

[7]

BRUZE M, 1987, ACTA DERM-VENEREOL, V67, P315

[8] CONTACT ALLERGY TO THE ACTIVE INGREDIENTS OF KATHON CG [J].

BRUZE, M ;

DAHLQUIST, I ;

FREGERT, S ;

GRUVBERGER, B ;

PERSSON, K .

CONTACT DERMATITIS, 1987, 16 (04) :183-188

[9]

CROW WD, 1969, AUST J CHEM, V22, P763

[10] An update of the risk assessment for methylchloroisothiazolinone methylisothiazolinone (MCI/MI) with focus on rinse-off products [J].

Fewings, J ;

Menné, T .

CONTACT DERMATITIS, 1999, 41 (01) :1-13

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