Characterization and superoxide dismutase activity of copper(II) complexes of 6A,6X-difunctionalized beta-cyclodextrins

被引：21

作者：

Bonomo, RP ^{[1
]}

Conte, E ^{[1
]}

DeGuidi, G ^{[1
]}

Maccarrone, G ^{[1
]}

Rizzarelli, E ^{[1
]}

Vecchio, G ^{[1
]}

机构：

[1] IST STUDIO SOSTANZE NAT INTERESSE ALIMENTARE & CH, I-95125 CATANIA, ITALY

来源：

JOURNAL OF THE CHEMICAL SOCIETY-DALTON TRANSACTIONS | 1996年 / 23期

关键词：

D O I：

10.1039/dt9960004351

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Thermodynamic and EPR spectroscopic measurements were carried out in aqueous solution on copper(II) complexes of beta-cyclodextrins 6A,6X-difunctionalized (X = B, C or D) with histamine (imidazole-4-ethanamine). The O-2(-) scavenger activity of these systems was determined through both enzymatic and photohaemolysis assays. An attempt was made to correlate the scavenger ability with the geometrical features of the copper(II) complexes. The determination of the stability constants of the copper(II) complexes with 6A,6B-bis[2-(imidazol-4-yl)ethylamino]-6A,6B-dideoxy-beta-cyclodextrin revealed the speciation under the experimental conditions.

引用

页码：4351 / 4355

页数：5

共 26 条

[1] SYNTHESIS AND REACTIVITY OF COBALT(III) COMPLEXES BEARING PRIMARY-SIDE AND SECONDARY-SIDE CYCLODEXTRIN BINDING-SITES - A TALE OF 2 CDS [J].

AKKAYA, EU ;

CZARNIK, AW .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1988, 110 (25) :8553-8554

[2] MIXED-METAL COMPLEXES IN SOLUTION .3. THERMODYNAMIC STUDY OF HETEROBINUCLEAR COPPER(II)-L-HISTIDINE AND COPPER(II)-L-HISTAMINE COMPLEXES IN AQUEOUS-SOLUTION [J].

AMICO, P ;

ARENA, G ;

DANIELE, PG ;

OSTACOLI, G ;

RIZZARELLI, E ;

SAMMARTANO, S .

INORGANIC CHEMISTRY, 1981, 20 (03) :772-777

[3]

[Anonymous], PHOTOCHEMISTRY

[4] NONLINEAR LEAST-SQUARES APPROACH TO THE REFINEMENT OF ALL PARAMETERS INVOLVED IN ACID-BASE TITRATIONS [J].

ARENA, G ;

RIZZARELLI, E ;

SAMMARTANO, S ;

RIGANO, C .

TALANTA, 1979, 26 (01) :1-14

[5]

Beauchamp C., 1971, ANAL BIOCHEM, V44, P276, DOI DOI 10.1016/0003-2697(71)90370-8

[6] LIGAND-FIELD MODEL FOR THE HYPERFINE INTERACTION IN THE EPR-SPECTRA OF LOW-SYMMETRY TRANSITION-METAL COMPLEXES [J].

BENCINI, A ;

GATTESCHI, D .

JOURNAL OF MAGNETIC RESONANCE, 1979, 34 (03) :653-656

[7]

Bender M.L., 1978, Cyclodextrin Chemistry

[8] COPPER(II) COMPLEXES OF DIASTEREOISOMERIC DIPEPTIDES IN AQUEOUS-SOLUTION - EFFECT OF SIDE-CHAIN GROUPS ON THE THERMODYNAMIC STEREOSELECTIVITY [J].

BONOMO, RP ;

CALI, R ;

CUCINOTTA, V ;

IMPELLIZZERI, G ;

RIZZARELLI, E .

INORGANIC CHEMISTRY, 1986, 25 (10) :1641-1646

[9] COORDINATION PROPERTIES OF 6-DEOXY-6-[1-(2-AMINO) ETHYLAMINO]-BETA-CYCLODEXTRIN AND THE ABILITY OF ITS COPPER(II) COMPLEX TO RECOGNIZE AND SEPARATE AMINO-ACID ENANTIOMERIC PAIRS [J].

BONOMO, RP ;

CUCINOTTA, V ;

DALLESSANDRO, F ;

IMPELLIZZERI, G ;

MACCARRONE, G ;

RIZZARELLI, E .

JOURNAL OF INCLUSION PHENOMENA AND MOLECULAR RECOGNITION IN CHEMISTRY, 1993, 15 (02) :167-180

[10] CONFORMATIONAL FEATURES AND COORDINATION PROPERTIES OF FUNCTIONALIZED CYCLODEXTRINS - FORMATION, STABILITY, AND STRUCTURE OF PROTON AND COPPER(II) COMPLEXES OF HISTAMINE-BEARING BETA-CYCLODEXTRIN IN AQUEOUS-SOLUTION [J].

BONOMO, RP ;

CUCINOTTA, V ;

DALESSANDRO, F ;

IMPELLIZZERI, G ;

MACCARRONE, G ;

VECCHIO, G ;

RIZZARELLI, E .

INORGANIC CHEMISTRY, 1991, 30 (13) :2708-2713

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