Fontan Patient with Plastic Bronchitis Treated Successfully Using Aerosolized Tissue Plasminogen Activator: A Case Report and Review of the Literature

被引：50

作者：

Do, Thomas B. ^{[1
]}

Chu, James M. ^{[1
]}

Berdjis, Farhouch ^{[1
]}

Anas, Nick G. ^{[1
]}

机构：

[1] Childrens Hosp Orange Cty, Orange, CA 92868 USA

来源：

PEDIATRIC CARDIOLOGY | 2009年 / 30卷 / 03期

关键词：

Fontan procedure; Plastic bronchitis; Tissue plasminogen activator; CHILDREN;

D O I：

10.1007/s00246-008-9312-2

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Plastic bronchitis is an uncommon condition characterized by the production of large pale bronchial casts that obstruct the tracheobronchial tree. The cellular content, cohesiveness, and often rubber-like consistency distinguish bronchial casts from the usual mucus plugs found with such disease states as asthma. Plastic bronchitis can be found secondary to many conditions, and a simplified classification scheme organizes it into two groups: an inflammatory type consisting of casts with an eosinophilic inflammatory infiltrate and an acellular type with a predominance of fibrin distinguished by its relative lack of cellular infiltrate, its mucin predominance, and its appearance only in children with congenital cyanotic heart disease. This report describes a 5-year-old girl who experienced plastic bronchitis 3 months after a Fontan procedure for hypoplastic left heart syndrome that was treated successfully with aerosolized tissue plasminogen activator.

引用

页码：352 / 355

页数：4

共 13 条

[1] Resolution of plastic bronchitis with atrial pacing in a patient with Fontan physiology [J].