Navigating and mining modENCODE data

被引：12

作者：

Boley, Nathan ^{[1
]}

Wan, Kenneth H. ^{[2
]}

Bickel, Peter J. ^{[3
]}

Celniker, Susan E. ^{[2
]}

机构：

[1] Univ Calif Berkeley, Dept Biostat, Berkeley, CA 94720 USA

[2] Univ Calif Berkeley, Lawrence Berkeley Natl Lab, Dept Genome Dynam, Berkeley, CA 94720 USA

[3] Univ Calif Berkeley, Dept Stat, Berkeley, CA 94720 USA

来源：

METHODS | 2014年 / 68卷 / 01期

关键词：

modENCODE; Mining; Drosophila; Transcription; Chromatin; CHIP-SEQ EXPERIMENTS; FULL-LENGTH CDNAS; GENE-EXPRESSION; DNA; SEQUENCE; TRANSCRIPTS; MICRORNAS;

D O I：

10.1016/j.ymeth.2014.03.007

中图分类号：

Q5 [生物化学];

学科分类号：

070307 [化学生物学];

摘要：

modENCODE was a 5 year NHGRI funded project (2007-2012) to map the function of every base in the genomes of worms and flies characterizing positions of modified histones and other chromatin marks, origins of DNA replication, RNA transcripts and the transcription factor binding sites that control gene expression. Here we describe the Drosophila modENCODE datasets and how best to access and use them for genome wide and individual gene studies. (C) 2014 Elsevier Inc. All rights reserved.

引用

页码：38 / 47

页数：10

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