Analysis of strychnine from detoxified Strychno nux-vomica seeds using liquid chromatography-electro spray mass spectrometry

被引：27

作者：

Choi, YH

Sohn, YM

Kim, CY

Oh, KY

Kim, J ^{[1
]}

机构：

[1] Seoul Natl Univ, Coll Pharm, Seoul 151742, South Korea

[2] Seoul Natl Univ, Pharmaceut Sci Res Inst, Seoul 151742, South Korea

[3] GreenTek21 Co Ltd, Seoul 121742, South Korea

来源：

JOURNAL OF ETHNOPHARMACOLOGY | 2004年 / 93卷 / 01期

关键词：

Strychno nux-vomica seeds; detoxification; HPLC-ESI/MS;

D O I：

10.1016/j.jep.2004.03.038

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The content of strychnine from Strychno nux-vomica seeds was analyzed and compared to processed seeds by the HPLC-ESI/MS method. Using this technique, levels as low as 1 ng of strychnine were detected. In contrast to conventional UV detectors, this method also made it possible to discriminate brucine. This study resulted in finding the content of strychnine in detoxified seeds to be one tenth of unprocessed Strychno nux-vomica seeds. (C) 2004 Elsevier Ireland Ltd. All rights reserved.

引用

页码：109 / 112

页数：4