Recurrence Quantification Analysis at work: Quasi-periodicity based interpretation of gait force profiles for patients with Parkinson disease

被引:41
作者
Afsar, Ozgur [1 ,3 ]
Tirnakli, Ugur [1 ,2 ]
Marwan, Norbert [3 ]
机构
[1] Ege Univ, Fac Sci, Dept Phys, TR-35100 Izmir, Turkey
[2] Ctr Brasileiro Pesquisas Fis, Rua Dr Xavier Sigaud 150, BR-22290180 Rio De Janeiro, RJ, Brazil
[3] Potsdam Inst Climate Impact Res, Telegraphenberg A 31, D-14473 Potsdam, Germany
关键词
FRACTAL DYNAMICS; SYNCHRONIZATION; SCALE; FLUCTUATION; INSTABILITY; RESOURCE; RHYTHM; PLOTS;
D O I
10.1038/s41598-018-27369-2
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
070301 [无机化学]; 070403 [天体物理学]; 070507 [自然资源与国土空间规划学]; 090105 [作物生产系统与生态工程];
摘要
In this letter, making use of real gait force profiles of healthy and patient groups with Parkinson disease which have different disease severity in terms of Hoehn-Yahr stage, we calculate various heuristic complexity measures of the recurrence quantification analysis (RQA). Using this technique, we are able to evince that entropy, determinism and average diagonal line length (divergence) measures decrease (increases) with increasing disease severity. We also explain these tendencies using a theoretical model (based on the sine-circle map), so that we clearly relate them to decreasing degree of irrationality of the system as a course of gait's nature. This enables us to interpret the dynamics of normal/pathological gait and is expected to increase further applications of this technique on gait timings, gait force profiles and combinations of them with various physiological signals.
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页数:12
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