Effects of stacking on the configurations and elasticity of single-stranded nucleic acids

被引：36

作者：

Buhot, A ^{[1
]}

Halperin, A ^{[1
]}

机构：

[1] CEA Grenoble, UJF, CNRS, UMR 5819, F-38054 Grenoble 9, France

来源：

PHYSICAL REVIEW E | 2004年 / 70卷 / 02期

关键词：

D O I：

10.1103/PhysRevE.70.020902

中图分类号：

O35 [流体力学]; O53 [等离子体物理学];

学科分类号：

070204 ; 080103 ; 080704 ;

摘要：

Stacking interactions in single-stranded nucleic acids give rise to configurations of an annealed rod-coil multiblock copolymer. Theoretical analysis identifies the following resulting signatures for long homopolynucleotides: a nonmonotonic dependence of size on temperature, the corresponding effects on cyclization and a plateau in the extension force law. Explicit numerical results for polydeoxyadenylate [poly(dA)] and polyriboadenylate [poly(rU)] are presented.

引用

页数：4

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