Immunology of implantation

被引：20

作者：

Mor, G ^{[1
]}

Abrahams, VM ^{[1
]}

机构：

[1] Yale Univ, Sch Med, Dept Obstet & Gynecol, Reprod Immunol Unit, New Haven, CT 06520 USA

来源：

IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA | 2002年 / 22卷 / 03期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/S0889-8561(02)00009-7

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Important reproductive events including implantation, trophoblast invasion, placental development, and immune protection are regulated by the immune system at the maternal-fetal interface. This maternal-fetal immune interaction is complex, and it is difficult to perceive the whole process based on one mechanism of action. Clearly, there are multiple mechanisms for the induction of peripheral and local tolerance during pregnancy that prevent fetal rejection while maintaining a strong and active immune surveillance against viral or bacterial infections, which may endanger the successful outcome and the survival of the species.

引用

页码：545 / +

页数：22

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