Vagus nerve stimulation for refractory status epilepticus

被引：39

作者：

De Herdt, Veerle ^{[1
]}

Waterschoot, Liesbeth ^{[1
]}

Vonck, Kristl ^{[1
]}

Dermaut, Bart ^{[1
]}

Verhelst, Helene ^{[2
]}

Van Coster, Rudy ^{[2
]}

De Jaeger, Annick ^{[3
]}

Van Roost, Dirk ^{[4
]}

Boon, Paul ^{[1
]}

机构：

[1] Ghent Univ Hosp, Reference Ctr Refractory Epilepsy, Dept Neurol, B-9000 Ghent, Belgium

[2] Ghent Univ Hosp, Dept Pediat, Div Pediat Neurol, B-9000 Ghent, Belgium

[3] Ghent Univ Hosp, Intens Care Unit, B-9000 Ghent, Belgium

[4] Ghent Univ Hosp, Dept Neurosurg, B-9000 Ghent, Belgium

来源：

EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY | 2009年 / 13卷 / 03期

关键词：

Vagus nerve stimulation; Non-convulsive status epilepticus; Refractory status epilepticus; Children; SEIZURES;

D O I：

10.1016/j.ejpn.2008.05.004

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

100204 [神经病学];

摘要：

We report on the long-term follow-up of a patient with refractory non-convulsive SE who was successfully treated with VNS. A 7-year old girl with a medical history of thrombosis in the right internal cerebral vein and right thalamic bleeding 8 days after birth, developed epilepsy at the age of 13 months. At the age of 6 she presented with a refractory non-convulsive SE. A vagus nerve stimulator was placed after 11 days of thiopental-induced coma. Three days after VNS implantation, the thiopental-induced coma was successfully withdrawn and electroencephalography showed normalization one week after start of VNS. After a follow-up of 13 months she remains seizure-free and AEDs have been partially tapered. This case illustrates a potential acute abortive effect with sustained long-term seizure reduction of VNS in a 7-year old girl who presented with refractory non-convulsive SE. (C) 2008 European Paediatric Neurology Society. Published by Elsevier Ltd. All rights reserved.

引用

页码：286 / 289

页数：4

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