Repetitive transcranial magnetic stimulation of the supplementary motor area (SMA) degrades bimanual movement control in humans

被引：140

作者：

Serrien, DJ ^{[1
]}

Strens, LHA ^{[1
]}

Oliviero, A ^{[1
]}

Brown, P ^{[1
]}

机构：

[1] Inst Neurol, Sobell Dept Neurophysiol, London WC1N 3BG, England

来源：

NEUROSCIENCE LETTERS | 2002年 / 328卷 / 02期

基金：

英国医学研究理事会;

关键词：

synchronization; interlimb coordination; electroencephalography;

D O I：

10.1016/S0304-3940(02)00499-8

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Moving the upper limbs at a common tempo according to an in-phase or anti-phase mode represents elementary coordination dynamics. Previously, the role of the supplementary motor area (SMA) has been emphasized for successful production of these patterns. The objective of this study was to investigate whether repetitive transcranial magnetic stimulation (rTMS) of the SMA at 5 Hz can interfere with these isofrequency configurations in the post-stimulation stage. Results showed a deterioration of temporal control as a function of coordinative complexity. This effect was associated with a decrease in the functional coupling between the primary motor cortices, as measured by electroencephalographic coherence. These data suggest that rTMS of the SMA can modify interhemispheric communication and accordingly modulate interlimb behavior. (C) 2002 Published by Elsevier Science Ireland Ltd.

引用

页码：89 / 92

页数：4

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