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Genetic interactions of Hox genes in limb development: learning from compound mutants

被引：72
作者：
Rijli, FM
Chambon, P
机构：
[1] Inst. Genet. Biol. Molec. et Cell., CNRS/INSERM/ULP, Collège de France, Communaute Urbaine de Strasbourg
来源：
CURRENT OPINION IN GENETICS & DEVELOPMENT | 1997年 / 7卷 / 04期
关键词：
D O I：
10.1016/S0959-437X(97)80074-3
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
The recent generation of mice harboring multiple mutations in Hox genes has highlighted the role of these genes in controlling growth and patterning of the limb bud. Tt le study of the phenotypes has not only revealed a complex network of genetic interactions among paralogous and non-paralogous Abdominal-B-related Hox genes but has also refined our understanding of their function.
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页码：481 / 487
页数：7
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