Enzymology - Not just an active site

被引：8

作者：

Banner, DW ^{[1
]}

机构：

[1] F Hoffmann La Roche & Co Ltd, Dept Chem Technol, Div Pharmaceut Res, CH-4070 Basel, Switzerland

来源：

NATURE | 2000年 / 404卷 / 6777期

关键词：

D O I：

10.1038/35006540

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Enzymes are often regulated through so-called ‘exosites’ - regions on their surface that are distant from their active sites. New information about the exosites of two enzymes involved in regulating blood clotting, thrombin and thrombomodulin, offers further insight into the coagulation process, and may allow the further development of anticoagulants.

引用

页码：449 / 450

页数：2

共 9 条

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