Consensus Statement: First International Workshop on Anesthetics and Alzheimer's Disease

被引:123
作者
Baranov, Dmitri [1 ]
Bickler, Philip E. [2 ]
Crosby, Gregory J. [3 ]
Culley, Deborah J. [3 ]
Eckenhoff, Maryellen F. [1 ]
Eckenthoff, Roderic G. [1 ]
Hogan, Kirk J. [4 ]
Jevtovic-Todorovic, Vesna [5 ]
Palotas, Andras [6 ]
Perouansky, Misha [4 ]
Planel, Emmanuel [7 ]
Silverstein, Jeffrey H. [8 ]
Wei, Huafeng [1 ]
Whittington, Robert A. [9 ]
Xie, Zhongcong [10 ]
Zuo, Zhiyi [5 ]
机构
[1] Univ Penn, Sch Med, Dept Anesthesiol & Crit Care, Philadelphia, PA 19104 USA
[2] Univ Calif San Francisco, Dept Anesthesia, Med Ctr, San Francisco, CA 94143 USA
[3] Harvard Univ, Brigham & Womens Hosp, Sch Med, Dept Anesthesiol, Boston, MA 02115 USA
[4] Univ Wisconsin, Dept Anesthesiol, Madison, WI USA
[5] Univ Virginia Hlth Syst, Dept Anesthesiol, Charlottesville, VA USA
[6] Asklepios Med Bt, Szeged, Hungary
[7] Columbia Univ, Dept Pathol, Taub Inst Alzheimers Dis Res, Med Ctr, New York, NY USA
[8] NYU, Dept Anesthesiol, Mt Sinai Sch Med, New York, NY 10016 USA
[9] Columbia Univ, Dept Anesthesiol, Med Ctr, New York, NY USA
[10] Harvard Univ, Massachusetts Gen Hosp, Sch Med, Dept Anesthesia & Crit Care, Boston, MA USA
关键词
POSTOPERATIVE COGNITIVE DYSFUNCTION; ISOFLURANE INDUCES APOPTOSIS; BETA-PROTEIN-LEVELS; NONCARDIAC SURGERY; RAT-BRAIN; ACTIVATION; EXPOSURE; IMPAIRMENT; DEMENTIA; CALCIUM;
D O I
10.1213/ane.0b013e318199dc72
中图分类号
R614 [麻醉学];
学科分类号
100217 [麻醉学];
摘要
In order to review the current status of the potential relationship between anesthesia and Alzheimer's disease, a group of scientists recently met in Philadelphia for a full day of presentations and discussions. This special article represents a consensus view on the possible link between Alzheimer's disease and anesthesia and the steps required to test this more definitively.
引用
收藏
页码:1627 / 1630
页数:4
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