Genetics and neuropsychiatric disorders: Genome-wide, yet narrow

被引:7
作者
de Vries, Petrus J. [1 ,2 ]
机构
[1] Cambridgeshire & Peterborough NHS Fdn Trust, Neurodev Serv, Cambridge, England
[2] Univ Cambridge, Dev Psychiat Sect, Cambridge, England
关键词
AUTISM; MUTATIONS;
D O I
10.1038/nm0809-850
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
070307 [化学生物学]; 071010 [生物化学与分子生物学];
摘要
引用
收藏
页码:850 / 851
页数:3
相关论文
共 12 条
[1]
Advances in autism genetics: on the threshold of a new neurobiology [J].
Abrahams, Brett S. ;
Geschwind, Daniel H. .
NATURE REVIEWS GENETICS, 2008, 9 (05) :341-355
[2]
Investigating genotype-phenotype relationships in Rett syndrome using an international data set [J].
Bebbington, A. ;
Anderson, A. ;
Ravine, D. ;
Fyfe, S. ;
Pineda, M. ;
de Klerk, N. ;
Ben-Zeev, B. ;
Yatawara, N. ;
Percy, A. ;
Kaufmann, W. E. ;
Leonard, H. .
NEUROLOGY, 2008, 70 (11) :868-875
[3]
Targeted rescue of a destabilized mutant of p53 by an in silico screened drug [J].
Boeckler, Frank M. ;
Joerger, Andreas C. ;
Jaggi, Gaurav ;
Rutherford, Trevor J. ;
Veprintsev, Dmitry B. ;
Fersht, Alan R. .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2008, 105 (30) :10360-10365
[4]
Neuro-epileptic determinants of autism spectrum disorders in tuberous sclerosis complex [J].
Bolton, PF ;
Park, RJ ;
Higgins, JNP ;
Griffiths, PD ;
Pickles, A .
BRAIN, 2002, 125 :1247-1255
[5]
The tuberous sclerosis complex proteins - a GRIPP on cognition and neurodevelopment [J].
de Vries, Petrus J. ;
Howe, Christopher J. .
TRENDS IN MOLECULAR MEDICINE, 2007, 13 (08) :319-326
[6]
Mutations in the gene encoding the synaptic scaffolding protein SHANK3 are associated with autism spectrum disorders [J].
Durand, Christelle M. ;
Betancur, Catalina ;
Boeckers, Tobias M. ;
Bockmann, Juergen ;
Chaste, Pauline ;
Fauchereau, Fabien ;
Nygren, Gudrun ;
Rastam, Maria ;
Gillberg, I. Carina ;
Anckarsater, Henrik ;
Sponheim, Eili ;
Goubran-Botros, Hany ;
Delorme, Richard ;
Chabane, Nadia ;
Mouren-Simeoni, Marie-Christine ;
de Mas, Philippe ;
Bieth, Eric ;
Roge, Bernadette ;
Heron, Delphine ;
Burglen, Lydie ;
Gillberg, Christopher ;
Leboyer, Marion ;
Bourgeron, Thomas .
NATURE GENETICS, 2007, 39 (01) :25-27
[7]
DEPRESSION GENE Back to the Drawing Board for Psychiatric Genetics [J].
Holden, Constance .
SCIENCE, 2009, 324 (5935) :1628-1628
[8]
Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism [J].
Jamain, S ;
Quach, H ;
Betancur, C ;
Råstam, M ;
Colineaux, C ;
Gillberg, IC ;
Soderstrom, H ;
Giros, B ;
Leboyer, M ;
Gillberg, C ;
Bourgeron, T ;
Gillberg, C ;
Råstam, M ;
Gillberg, C ;
Nydén, A ;
Söderström, H ;
Leboyer, M ;
Betancur, C ;
Philippe, A ;
Giros, B ;
Colineaux, C ;
Cohen, D ;
Chabane, N ;
Mouren-Siméoni, MC ;
Brice, A ;
Sponheim, E ;
Spurkland, I ;
Skjeldal, OH ;
Coleman, M ;
Pearl, PL ;
Cohen, IL ;
Tsiouris, J ;
Zappella, M ;
Menchetti, G ;
Pompella, A ;
Aschauer, H ;
Van Maldergem, L .
NATURE GENETICS, 2003, 34 (01) :27-29
[9]
Structural biology of the tumor suppressor p53 [J].
Joerger, Andreas C. ;
Fersht, Alan R. .
ANNUAL REVIEW OF BIOCHEMISTRY, 2008, 77 :557-582
[10]
Distinct effects of single amino-acid changes to tuberin on the function of the tuberin-hamartin complex [J].
Nellist, M ;
Sancak, O ;
Goedbloed, MA ;
Rohe, C ;
van Netten, D ;
Mayer, K ;
Tucker-Williams, A ;
van den Ouweland, AMW ;
Halley, DJJ .
EUROPEAN JOURNAL OF HUMAN GENETICS, 2005, 13 (01) :59-68