Silence in the germ

被引:21
作者
Pirrotta, V [1 ]
机构
[1] Univ Geneva, Dept Zool, CH-1211 Geneva, Switzerland
关键词
D O I
10.1016/S0092-8674(02)00967-4
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Gene expression in C. elegans germline cells is subject to strict controls. A set of MES proteins, including SET domain proteins and two homologs of Polycomb group proteins, establish an epigenetically transmitted silenced state that affects X chromosome gene expression.
引用
收藏
页码:661 / 664
页数:4
相关论文
共 18 条
[1]   Regulation of the different chromatin states of autosomes and X chromosomes in the germ line of C-elegans [J].
Fong, YY ;
Bender, L ;
Wang, WC ;
Strome, S .
SCIENCE, 2002, 296 (5576) :2235-2238
[2]   Mechanisms of transcriptional memory [J].
Francis, NJ ;
Kingston, RE .
NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2001, 2 (06) :409-421
[3]  
Garvin C, 1998, GENETICS, V148, P167
[4]  
Holdeman R, 1998, DEVELOPMENT, V125, P2457
[5]  
Kelly WG, 1998, DEVELOPMENT, V125, P2451
[6]  
Kelly WG, 2002, DEVELOPMENT, V129, P479
[7]  
Korf I, 1998, DEVELOPMENT, V125, P2469
[8]   The PIE-1 protein and germline specification in C-elegans embryos [J].
Mello, CC ;
Schubert, C ;
Draper, B ;
Zhang, W ;
Lobel, R ;
Priess, JR .
NATURE, 1996, 382 (6593) :710-712
[9]   Set9, a novel histone H3 methyltransferase that facilitates transcription by precluding histone tail modifications required for heterochromatin formation [J].
Nishioka, K ;
Chuikov, S ;
Sarma, K ;
Erdjument-Bromage, H ;
Allis, CD ;
Tempst, P ;
Reinberg, D .
GENES & DEVELOPMENT, 2002, 16 (04) :479-489
[10]   The Polycomb-group gene Ezh2 is required for early mouse development [J].
O'Carroll, D ;
Erhardt, S ;
Pagani, M ;
Barton, SC ;
Surani, MA ;
Jenuwein, T .
MOLECULAR AND CELLULAR BIOLOGY, 2001, 21 (13) :4330-4336