Novel resistance-nodulation-cell division efflux system AdeDE in Acinetobacter genomic DNA group 3

被引：56

作者：

Chau, SL ^{[1
]}

Chu, YW ^{[1
]}

Houang, ETS ^{[1
]}

机构：

[1] Chinese Univ Hong Kong, Publ Hlth Lab Ctr, Dept Hlth, Dept Microbiol, Hong Kong, Hong Kong, Peoples R China

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2004年 / 48卷 / 10期

关键词：

D O I：

10.1128/AAC.48.10.4054-4055.2004

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Resistance-nodulation-cell division type efflux pump AdeDE was identified in acinetobacters belonging to genomic DNA group 3. Inactivation of adeE showed that it may be responsible for reduced susceptibility to amikacin, ceftazidime, chloramphenicol, ciprofloxacin, erythromycin, ethidium bromide, meropenem, rifampin, and tetracycline. However, unlike what was found for other similar efflux systems, the open reading frame for the outer membrane component was not found downstream of the adeDE gene cluster.

引用

页码：4054 / 4055

页数：2

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