Generation of aza-ortho-xylylenes via ring opening of 2-(2-acylaminophenyl)aziridines:: Application in the construction of the communesin ring system

被引：80

作者：

Crawley, Seth L. ^{[1
]}

Funk, Raymond L. ^{[1
]}

机构：

[1] Penn State Univ, Dept Chem, University Pk, PA 16802 USA

来源：

ORGANIC LETTERS | 2006年 / 8卷 / 18期

关键词：

D O I：

10.1021/ol061461d

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new protocol for generating aza-ortho-xylylenes via acid-catalyzed or fluoride-promoted ring opening of 2-(2-acylaminophenyl) aziridines is described. This methodology has been exploited in the rapid construction of a hexacyclic substructure of communesin B.

引用

页码：3995 / 3998

页数：4

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