Bacterial pathogens as biological weapons and agents of bioterrorism

被引:100
作者
Greenfield, RA
Drevets, DA
Machado, LJ
Voskuhl, GW
Bronze, MS
机构
[1] Oklahoma City A Med Ctr, Infect Dis Sect, Oklahoma City, OK 73104 USA
[2] Univ Oklahoma, Hlth Sci Ctr, Dept Med, Infect Dis Sect, Oklahoma City, OK 73190 USA
关键词
anthrax; bioterrorism; brucellosis; glanders; melioidosis; plague; Q fever; tularemia;
D O I
10.1097/00000441-200206000-00003
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Bacterial pathogens have been identified as agents that have been, or could be, used as weapons of biological warfare and/or biological terrorism. These agents are relatively easily obtained, prepared, and dispersed, either as weapons of mass destruction or for more limited terrorist attacks. Although phylogenetically diverse, these agents all have the potential for aerosol dissemination. Physicians in the United States and most of the developed world have never encountered most of these agents and the diseases they produce. Public health programs must be prepared, and individual primary care providers must be able to recognize, diagnose, treat, and prevent infection with these agents.
引用
收藏
页码:299 / 315
页数:17
相关论文
共 83 条
[1]  
Centers for Disease Control and Prevention, 2000, MMWR Recomm Rep, V49, P1
[2]  
[Anonymous], ESCHERICHIA COLI O15
[3]  
[Anonymous], CHOLERA
[4]   PATHOGENESIS OF RICKETTSIAL INFECTIONS EMPHASIS ON Q-FEVER [J].
BACA, OG .
EUROPEAN JOURNAL OF EPIDEMIOLOGY, 1991, 7 (03) :222-228
[5]   Fatal inhalational anthrax in a 94-year-old Connecticut woman [J].
Barakat, LA ;
Quentzel, HL ;
Jernigan, JA ;
Kirschke, DL ;
Griffith, K ;
Spear, SM ;
Kelley, K ;
Barden, D ;
Mayo, D ;
Stephens, DS ;
Popovic, T ;
Marston, C ;
Zaki, SR ;
Guarner, J ;
Shieh, WJ ;
Carver, HW ;
Meyer, RF ;
Swerdlow, DL ;
Mast, EE ;
Hadler, JL .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2002, 287 (07) :863-868
[6]  
Bell David M, 2002, Emerg Infect Dis, V8, P222
[7]   Death due to bioterrorism-related inhalational anthrax - Report of 2 patients [J].
Borio, L ;
Frank, D ;
Mani, V ;
Chiriboga, C ;
Pollanen, M ;
Ripple, M ;
Ali, S ;
DiAngelo, C ;
Lee, J ;
Arden, J ;
Titus, J ;
Fowler, D ;
O'Toole, T ;
Masur, H ;
Bartlett, J ;
Inglesby, T .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2001, 286 (20) :2554-2559
[8]   Identification of the cellular receptor for anthrax toxin [J].
Bradley, KA ;
Mogridge, J ;
Mourez, M ;
Collier, RJ ;
Young, JAT .
NATURE, 2001, 414 (6860) :225-229
[9]   Index case of fatal inhalational anthrax due to bioterrorism in the United States [J].
Bush, LM ;
Abrams, BH ;
Beall, A ;
Johnson, CC .
NEW ENGLAND JOURNAL OF MEDICINE, 2001, 345 (22) :1607-1610
[10]   YERSINIA-PESTIS INFECTION IN VIETNAM .2. QUANTITATIVE BLOOD CULTURES AND DETECTION OF ENDOTOXIN IN CEREBROSPINAL-FLUID OF PATIENTS WITH MENINGITIS [J].
BUTLER, T ;
LEVIN, J ;
LINH, NN ;
CHAU, DM ;
ADICKMAN, M ;
ARNOLD, K .
JOURNAL OF INFECTIOUS DISEASES, 1976, 133 (05) :493-499