Simultaneous Liver-Kidney Transplantation in the MELD Era

被引:16
作者
Bloom, Roy D. [1 ]
Bleicher, Melissa [1 ]
机构
[1] Univ Penn, Renal Electrolyte & Hypertens Div, Dept Med, Philadelphia, PA 19104 USA
关键词
Transplant; Model of end-stage liver disease (MELD); Simultaneous liver-kidney (SLK) transplants; Orthotopic liver transplant (OLT); Acute kidney injury (AKI); PRETRANSPLANT RENAL-FUNCTION; HEPATITIS-C; HEPATORENAL-SYNDROME; CONSENSUS CONFERENCE; WAITING TIME; SURVIVAL; FAILURE; DISEASE; OUTCOMES; IMPACT;
D O I
10.1053/j.ackd.2009.05.005
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
100201 [内科学]; 100221 [泌尿外科学];
摘要
Impaired kidney function is common in liver transplant candidates and portends heightened risk for both postoperative chronic kidney disease and mortality. The weighting of serum creatinine in the Model of End-stage Liver Disease classification for liver allocation has been accompanied by a proliferation of simultaneous liver-kidney transplants in recent years. In the absence of standardized criteria for allocating kidneys in this setting, there is a wide variation in combined organ transplants across transplant centers. This review discusses the issues surrounding simultaneous liver-kidney transplantation and proposes a strategy for selecting patients to receive both organs. (C) 2009 by the National Kidney Foundation, Inc. All rights reserved.
引用
收藏
页码:268 / 277
页数:10
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