Thermal ablation therapy for hepatocellular carcinoma

被引:82
作者
Ahmed, M [1 ]
Goldberg, SN [1 ]
机构
[1] Harvard Univ, Sch Med, Beth Israel Deaconess Med Ctr, Minimally Invas Tumor Therapy Lab,Dept Radiol, Boston, MA 02215 USA
关键词
lasers; liver neoplasms; chemotherapeutic infusion; radiofrequency (RF) ablation; ultrasound; (US); focused; therapeutic;
D O I
10.1016/S1051-0443(07)61791-6
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Thermal ablation strategies, including the use of radiofrequency, microwaves, lasers, and high-intensity focused ultrasound, are gaining increasing attention as an alternative to standard surgical therapies in the treatment of primary hepatocellular carcinoma. Benefits over surgical resection include the anticipated reduction in morbidity and mortality, low cost, suitability for real-time imaging guidance, ability to perform ablative procedures on an outpatient basis, and the potential application in a wider spectrum of patients-including those who are not surgical candidates. In this review, the authors examine the reported clinical success of each of these four therapies, potential complications, current limitations, and future directions of development.
引用
收藏
页码:S231 / S243
页数:13
相关论文
共 140 条
  • [1] LIVER-TUMOR ABLATION BY INTERSTITIAL LASER PHOTOCOAGULATION - REVIEW OF EXPERIMENTAL AND CLINICAL-STUDIES
    AMIN, Z
    BOWN, SG
    LEES, WR
    [J]. SEMINARS IN INTERVENTIONAL RADIOLOGY, 1993, 10 (02) : 88 - 100
  • [2] HEPATIC METASTASES - INTERSTITIAL LASER PHOTOCOAGULATION WITH REAL-TIME US MONITORING AND DYNAMIC CT EVALUATION OF TREATMENT
    AMIN, Z
    DONALD, JJ
    MASTERS, A
    KANT, R
    STEGER, AC
    BOWN, SG
    LEES, WR
    [J]. RADIOLOGY, 1993, 187 (02) : 339 - 347
  • [3] Asahara Toshimasa, 1998, Hiroshima Journal of Medical Sciences, V47, P125
  • [4] Asahara Toshimasa, 1998, Hiroshima Journal of Medical Sciences, V47, P151
  • [5] Aschoff AJ, 2001, J MAGN RESON IMAGING, V13, P57, DOI 10.1002/1522-2586(200101)13:1<57::AID-JMRI1009>3.0.CO
  • [6] 2-N
  • [7] Beppu T, 2001, Nihon Geka Gakkai Zasshi, V102, P390
  • [8] Beppu T, 2001, Gan To Kagaku Ryoho, V28, P1583
  • [9] BEPPU T, 1998, JPN J CANC CHEMOTHER, V25, P1358
  • [10] BROWN S, 1991, LASERS GASTROENTEROL, P37