hMG increases the yield of mature oocytes and excellent-quality embryos in patients with a previous cycle having a high incidence of oocyte immaturity

被引:12
作者
Huddleston, Heather G. [1 ]
Jackson, Katharine V. [2 ]
Doyle, Joseph O. [2 ]
Racowsky, Catherine [2 ]
机构
[1] Univ Calif San Francisco, Ctr Reprod Hlth, Dept Obstet Gynecol & Reprod Sci, San Francisco, CA 94143 USA
[2] Harvard Univ, Sch Med, Brigham & Womens Hosp, Dept Obstet & Gynecol,Div Reprod Med, Boston, MA USA
关键词
IN-VITRO FERTILIZATION; CONTROLLED OVARIAN STIMULATION; DOWN-REGULATED WOMEN; RECOMBINANT HUMAN LH; LUTEINIZING-HORMONE SUPPLEMENTATION; RANDOMIZED CONTROLLED-TRIAL; ASSISTED REPRODUCTION; NORMOGONADOTROPHIC WOMEN; FSH; MULTICENTER;
D O I
10.1016/j.fertnstert.2009.02.039
中图分类号
R71 [妇产科学];
学科分类号
100211 [妇产科学];
摘要
In a selected group of patients with >20% oocyte immaturity during an IVF cycle with FSH alone, the addition of hMG to the stimulation protocol results in a higher yield of mature oocytes and excel lent-quality embryos. (Fertil Steril (R) 2009;92:946-9. (C)2009 by American Society for Reproductive Medicine.)
引用
收藏
页码:946 / 949
页数:4
相关论文
共 21 条
[1]
Clinical outcome following stimulation with highly purified hMG or recombinant FSH in patients undergoing IVF: a randomized assessor-blind controlled trial [J].
Andersen, Anders Nyboe ;
Devroey, Paul ;
Arce, Joan-Carles .
HUMAN REPRODUCTION, 2006, 21 (12) :3217-3227
[2]
THE ROLE OF LUTEINIZING-HORMONE IN HUMAN FOLLICLE DEVELOPMENT AND OOCYTE FERTILITY - EVIDENCE FROM IN-VITRO FERTILIZATION IN A WOMAN WITH LONG-STANDING HYPOGONADOTROPIC HYPOGONADISM AND USING RECOMBINANT HUMAN FOLLICLE-STIMULATING-HORMONE [J].
BALASCH, J ;
MIRO, F ;
BURZACO, I ;
CASAMITJANA, R ;
CIVICO, S ;
BALLESCA, JL ;
PUERTO, B ;
VANRELL, JA .
HUMAN REPRODUCTION, 1995, 10 (07) :1678-1683
[3]
Suppression of LH during ovarian stimulation:: analysing threshold values and effects on ovarian response and the outcome of assisted reproduction in down-regulated women stimulated with recombinant FSH [J].
Balasch, J ;
Vidal, E ;
Peñarrubia, J ;
Casamitjana, R ;
Carmona, F ;
Creus, M ;
Fábregues, F ;
Vanrell, JA .
HUMAN REPRODUCTION, 2001, 16 (08) :1636-1643
[4]
Balasch Juan, 2003, Reprod Biomed Online, V7, P35
[5]
Ovarian response and pregnancy outcome in poorresponder women:: a randomized controlled trial on the effect of luteinizing hormone supplementation on in vitro fertilization cycles [J].
Barrenetxea, Gorka ;
Agirregoikoa, Jon Ander ;
Jimenez, Maria Rosario ;
de larruzea, Arantza Lopez ;
Ganzabal, Teresa ;
Carbonero, Koldo .
FERTILITY AND STERILITY, 2008, 89 (03) :546-553
[6]
Recombinant human LH supplementation during GnRH antagonist administration in IVF/ICSI cycles:: a prospective randomized study [J].
Cédrin-Durnerin, I ;
Grange-Dujardin, D ;
Laffy, A ;
Parneix, I ;
Massin, N ;
Galey, J ;
Théron, L ;
Wolf, JP ;
Conord, C ;
Clément, P ;
Jayot, S ;
Hugues, JN .
HUMAN REPRODUCTION, 2004, 19 (09) :1979-1984
[7]
Evaluating the role of exogenous luteinizing hormone in poor responders undergoing in vitro fertilization with gonadotropin-releasing hormone antagonists [J].
Chung, K ;
Krey, L ;
Katz, J ;
Noyes, N .
FERTILITY AND STERILITY, 2005, 84 (02) :313-318
[8]
Recombinant human LH supplementation versus recombinant human FSH (rFSH) step-up protocol during controlled ovarian stimulation in normogonadotrophic women with initial inadequate ovarian response to rFSH. A multicentre, prospective, randomized controlled trial [J].
De Placido, G ;
Alviggi, C ;
Perino, A ;
Strina, I ;
Lisi, F ;
Fasolino, A ;
De Palo, R ;
Ranieri, A ;
Colacurci, N ;
Mollo, A .
HUMAN REPRODUCTION, 2005, 20 (02) :390-396
[9]
Role of periovulatory luteinizing hormone concentrations during assisted reproductive technology cycles stimulated exclusively with recombinant follicle-stimulating hormone [J].
Esposito, MA ;
Barnhart, KT ;
Coutifaris, C ;
Patrizio, P .
FERTILITY AND STERILITY, 2001, 75 (03) :519-524
[10]
Effects of recombinant human luteinizing hormone supplementation on ovarian stimulation and the implantation rate in down-regulated women of advanced reproductive age [J].
Fábregues, F ;
Creus, M ;
Peñarrubia, J ;
Manau, D ;
Vanrell, JA ;
Balasch, J .
FERTILITY AND STERILITY, 2006, 85 (04) :925-931