Isolation, synthesis, and antiplatelet aggregation activity of resveratrol 3-O-beta-D-glucopyranoside and related compounds

被引：164

作者：

Orsini, F ^{[1
]}

Pelizzoni, F ^{[1
]}

Verotta, L ^{[1
]}

Aburjai, T ^{[1
]}

Rogers, CB ^{[1
]}

机构：

[1] UNIV DURBAN WESTVILLE, DEPT CHEM, ZA-4000 DURBAN, SOUTH AFRICA

来源：

JOURNAL OF NATURAL PRODUCTS | 1997年 / 60卷 / 11期

关键词：

D O I：

10.1021/np970069t

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Resveratrol 3-O-beta-D-glucopyranoside (1) has been isolated from the seeds of Erythrophleum lasianthum (Caesalpinioidae, Leguminosae), a South African plant used in traditional medicine, and has shown antiplatelet aggregation activity. The synthesis of 1, related hydroxystilbenes, and their glucosides has been undertaken to provide larger quantities, for further biological evaluation, and has been accomplished via Wittig reactions followed by glucosylation under phase transfer catalysis.

引用

页码：1082 / 1087

页数：6

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