The mesh hypothesis of Golgi dynamics

被引:40
作者
Lorra, C
Huttner, WB
机构
[1] Univ Heidelberg, Dept Neurobiol, D-69120 Heidelberg, Germany
[2] Max Planck Inst Mol Cell Biol & Genet, D-01307 Dresden, Germany
关键词
D O I
10.1038/12939
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
The GTP-binding protein ARF induces the recruitment to the Golgi membrane of kinases that catalyse the synthesis of the lipid phosphatidylinositol-4,5-bisphosphate. This lipid acts as a binding site for certain actin-binding proteins, which may change the Golgi membrane skeleton to a form that allows membrane traffic.
引用
收藏
页码:E113 / E115
页数:3
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