On the wobble GoU and related pairs

被引:104
作者
Masquida, B [1 ]
Westhof, E [1 ]
机构
[1] CNRS, Inst Biol Mol & Cellulaire, F-67084 Strasbourg, France
关键词
A(+)oC; covariations; GoC; stacking; twist; wobble;
D O I
10.1017/S1355838200992082
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The wobble GoU pairs have been implicated in several biological processes where RNA molecules play a key role. We review the geometrical and conformational properties of wobble GoU pairs on the basis of available crystal structures of RNAs at high resolution. The similarities with the wobble A(+)oC pairs and UoU pairs are illustrated, while the differences with the recently discovered bifurcated G.U pairs are contrasted.
引用
收藏
页码:9 / 15
页数:7
相关论文
共 59 条
[1]   STRUCTURE OF THE P1 HELIX FROM GROUP-I SELF-SPLICING INTRONS [J].
ALLAIN, FHT ;
VARANI, G .
JOURNAL OF MOLECULAR BIOLOGY, 1995, 250 (03) :333-353
[2]   DIVALENT METAL-ION BINDING TO A CONSERVED WOBBLE PAIR DEFINING THE UPSTREAM SITE OF CLEAVAGE OF GROUP-I SELF-SPLICING INTRONS [J].
ALLAIN, FHT ;
VARANI, G .
NUCLEIC ACIDS RESEARCH, 1995, 23 (03) :341-350
[3]   Hydration of RNA base pairs [J].
Auffinger, P ;
Westhof, E .
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 1998, 16 (03) :693-707
[4]   Singly and bifurcated hydrogen-bonded base-pairs in tRNA anticodon hairpins and ribozymes [J].
Auffinger, P ;
Westhof, E .
JOURNAL OF MOLECULAR BIOLOGY, 1999, 292 (03) :467-483
[5]   STRUCTURE OF AN RNA DOUBLE HELIX INCLUDING URACIL-URACIL BASE-PAIRS IN AN INTERNAL LOOP [J].
BAEYENS, KJ ;
DEBONDT, HL ;
HOLBROOK, SR .
NATURE STRUCTURAL BIOLOGY, 1995, 2 (01) :56-62
[6]   Self-cleaving ribozymes of hepatitis delta virus RNA [J].
Been, MD ;
Wickham, GS .
EUROPEAN JOURNAL OF BIOCHEMISTRY, 1997, 247 (03) :741-753
[7]   Identification in a pseudoknot of a U•G motif essential for the regulation of the expression of ribosomal protein S15 [J].
Bénard, L ;
Mathy, N ;
Grunberg-Manago, M ;
Ehresmann, B ;
Ehresmann, C ;
Portier, C .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (05) :2564-2567
[8]   FLUORESCENCE-DETECTED STOPPED-FLOW WITH A PYRENE-LABELED SUBSTRATE REVEALS THAT GUANOSINE FACILITATES DOCKING OF THE 5' CLEAVAGE SITE INTO A HIGH FREE-ENERGY BINDING MODE IN THE TETRAHYMENA RIBOZYME [J].
BEVILACQUA, PC ;
LI, Y ;
TURNER, DH .
BIOCHEMISTRY, 1994, 33 (37) :11340-11348
[9]   Crystal structure of an alternating octamer r(GUAUGUA)dC with adjacent G center dot U wobble pairs [J].
Biswas, R ;
Wahl, MC ;
Ban, C ;
Sundaralingam, M .
JOURNAL OF MOLECULAR BIOLOGY, 1997, 267 (05) :1149-1156
[10]   Crystal structure of r(GUGUGUA)dC with tandem G center dot U/U center dot G wobble pairs with strand slippage [J].
Biswas, R ;
Sundaralingam, M .
JOURNAL OF MOLECULAR BIOLOGY, 1997, 270 (03) :511-519