The endogenous cannabinoid system and brain development

被引：261

作者：

Fernández-Ruiz, J ^{[1
]}

Berrendero, F ^{[1
]}

Hernáandez, ML ^{[1
]}

Ramos, JA ^{[1
]}

机构：

[1] Univ Complutense Madrid, Inst Univ Drogodependencias, Dept Bioquim & Biol Mol, Fac Med, E-28040 Madrid, Spain

来源：

TRENDS IN NEUROSCIENCES | 2000年 / 23卷 / 01期

关键词：

D O I：

10.1016/S0166-2236(99)01491-5

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Cannabinoid receptors and their endogenous ligands constitute a novel modulatory system that is involved in specific brain functions, such as nociception, control of movement, memory and neuroendocrine regulation. Recently, it has also been suggested that this system is involved in brain development. Studies have used a variety of techniques to elucidate the effects of cannabinoids during development, as well as to characterize the presence of elements of the endogenous cannabinoid system (receptors and ligands) in the developing brain. Collectively, they suggest that endocannabinoids participate in brain development through the activation of second-messenger coupled cannabinoid receptors.

引用

页码：14 / 20

页数：7

共 61 条

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