An open study of lamotrigine in refractory bipolar depression

被引：102

作者：

Kusumakar, V

Yatham, LN

机构：

[1] UNIV BRITISH COLUMBIA,DEPT PSYCHIAT,VANCOUVER,BC V6T 2A1,CANADA

[2] DALHOUSIE UNIV,DEPT PSYCHIAT,HALIFAX,NS B3H 3G2,CANADA

来源：

PSYCHIATRY RESEARCH | 1997年 / 72卷 / 02期

关键词：

lamotrigine; bipolar depression; divalproex sodium;

D O I：

10.1016/S0165-1781(97)00082-6

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

Bipolar depressed patients (n = 22) who were refractory to treatment with a combination of divalproex sodium (DVP) and another mood stabilizer or DVP and an antidepressant for 6 weeks were treated in an open naturalistic study with an addition of lamotrigine to DW. Sixteen out of 22 (72%) responded by the end of week 4 and none developed rash or switched to mania. The results of this preliminary study suggest that lamotrigine may be useful in bipolar depression. (C) 1997 Elsevier Science Ireland Ltd.

引用

页码：145 / 148

页数：4

共 14 条

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