Bacterial Martyrdom: Phagocytes Disabled by Type VI Secretion after Engulfing Bacteria

被引：7

作者：

Satchell, Karla J. F. ^{[1
]}

机构：

[1] Northwestern Univ, Feinberg Sch Med, Dept Immunol Microbiol, Chicago, IL 60611 USA

来源：

CELL HOST & MICROBE | 2009年 / 5卷 / 03期

关键词：

CHOLERAE RTX TOXIN; CROSS-LINKS ACTIN; PROTEIN SECRETION; SYSTEM; IDENTIFICATION; DOMAIN;

D O I：

10.1016/j.chom.2009.03.001

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

To colonize during disease and prevent consumption by environmental unicellular eukaryotes, bacteria often disrupt phagocytosis. In this issue, Ma et al. (2009) show that Vibrio cholerae delivers the actin-crosslinking T6SS effector VgrG-1 following phagocytosis. The effector then causes irreversible cytoskeleton destruction, leading to bystander protection of the extracellular bacterial population,

引用

页码：213 / 214

页数：2

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