DNA methylation database "MethDB": a user guide

被引：4

作者：

Grunau, C ^{[1
]}

Renault, E ^{[1
]}

Roizes, G ^{[1
]}

机构：

[1] Inst Genet Humains, Lab Sequences Repetees & Centromeres Humains, Montpellier, France

来源：

JOURNAL OF NUTRITION | 2002年 / 132卷 / 08期

关键词：

DNA methylation; MethDB; epigenetics; database; cancer; 5-methylcytosine;

D O I：

10.1093/jn/132.8.2435S

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 ;

摘要：

The DNA Methylation Database (MethDB; http://www.methdb.net) is a public database dedicated to DNA methylation. It attempts to store all data about DNA methylation in a common source. MethDB can be searched in different ways, ranging from a simple browse mode to detailed queries for sequence-specific DNA methylation profiles and patterns, total methylation content data or environmental conditions that can influence the methylation state of DNA. Currently, the database contains 2570 values for methylation content and 5278 methylation patterns and profiles for a total of 83 genes or loci. MethDB is an annotated database, and the scientific community is invited to submit their own data (submit@methdb.de).

引用

页码：2435S / 2439S

页数：5

共 10 条

[1] Methylation matters [J].

Costello, JF ;

Plass, C .

JOURNAL OF MEDICAL GENETICS, 2001, 38 (05) :285-303

[2]

COX R, 1985, BIOCHEM INT, V10, P63

[3]

CREUSOT F, 1982, J BIOL CHEM, V257, P2041

[4] A GENOMIC SEQUENCING PROTOCOL THAT YIELDS A POSITIVE DISPLAY OF 5-METHYLCYTOSINE RESIDUES IN INDIVIDUAL DNA STRANDS [J].

FROMMER, M ;

MCDONALD, LE ;

MILLAR, DS ;

COLLIS, CM ;

WATT, F ;

GRIGG, GW ;

MOLLOY, PL ;

PAUL, CL .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (05) :1827-1831

[5] MethTools - a toolbox to visualize and analyze DNA methylation data [J].

Grunau, C ;

Schattevoy, R ;

Mache, N ;

Rosenthal, A .

NUCLEIC ACIDS RESEARCH, 2000, 28 (05) :1053-1058

[6] MethDB - a public database for DNA methylation data [J].

Grunau, C ;

Renault, E ;

Rosenthal, A ;

Roizes, G .

NUCLEIC ACIDS RESEARCH, 2001, 29 (01) :270-274

[7] How are alkynes scrambled? [J].

Bunz, UHF .

SCIENCE, 2005, 308 (5719) :216-217

[8]

HOTCHKISS RD, 1948, J BIOL CHEM, V175, P315

[9] IMPROVED TOOLS FOR BIOLOGICAL SEQUENCE COMPARISON [J].

PEARSON, WR ;

LIPMAN, DJ .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (08) :2444-2448

[10]

Poirier L A, 1986, Adv Exp Med Biol, V206, P269

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