Serious infections due to methicillin-resistant Staphylococcus aureus: An evolving challenge for physicians

被引:35
作者
Falcone, Marco [1 ]
Serra, Pietro [1 ]
Venditti, Mario [1 ]
机构
[1] Univ Roma La Sapienza, Policlin Umberto I, Dipartimento Med Clin, I-00161 Rome, Italy
关键词
Methicillin resistance; Staphylococcus aureus; Community acquired; Health-care associated; Nosocomial infection; ANTIMICROBIAL SURVEILLANCE PROGRAM; PANTON-VALENTINE LEUKOCIDIN; NECROTIZING PNEUMONIA; HOSPITAL ADMISSION; UNITED-STATES; BACTEREMIA; VANCOMYCIN; EPIDEMIOLOGY; ENDOCARDITIS; TEICOPLANIN;
D O I
10.1016/j.ejim.2008.08.016
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Methicillin-resistant Staphylococcus aureus (MRSA) is a well-recognized major cause of nosocomial infection worldwide. During the past decade, however, the epidemiology of staphylococcal infections has partially changed, with an increase in the number of patients who acquire infections in the community. The changing epidemiology is a cause for concern among physicians, leading to an increase in the number of patients with infections due to MRSA diagnosed at hospital admission and in the emergency department. The aims of this article are to review the current state of knowledge regarding MRSA infections, to identify those factors which may help physicians to recognize the patients at high risk, and to manage these infections appropriately. (C) 2008 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.
引用
收藏
页码:343 / 347
页数:5
相关论文
共 51 条
[1]   The emergence of vancomycin-intermediate and vancomycin-resistant Staphylococcus aureus [J].
Appelbaum, PC .
CLINICAL MICROBIOLOGY AND INFECTION, 2006, 12 :16-23
[2]   Occurrence and antimicrobial resistance pattern comparisons among bloodstream infection isolates from the SENTRY Antimicrobial Surveillance Program (1997-2002) [J].
Biedenbach, DJ ;
Moet, GJ ;
Jones, RN .
DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, 2004, 50 (01) :59-69
[3]   EARLY TERMINATION OF A PROSPECTIVE, RANDOMIZED TRIAL COMPARING TEICOPLANIN AND FLUCLOXACILLIN FOR TREATING SEVERE STAPHYLOCOCCAL INFECTIONS [J].
CALAIN, P ;
KRAUSE, KH ;
VAUDAUX, P ;
AUCKENTHALER, R ;
LEW, D ;
WALDVOGEL, F ;
HIRSCHEL, B .
JOURNAL OF INFECTIOUS DISEASES, 1987, 155 (02) :187-191
[4]   National Nosocomial Infections Surveillance (NNIS) System Report, data summary from January 1992 through June 2004, issued October 2004 [J].
Cardo, D ;
Horan, T ;
Andrus, M ;
Dembinski, M ;
Edwards, J ;
Peavy, G ;
Tolson, J ;
Wagner, D .
AMERICAN JOURNAL OF INFECTION CONTROL, 2004, 32 (08) :470-485
[5]   The changing epidemiology of Staphylococcus aureus? [J].
Chambers, HF .
EMERGING INFECTIOUS DISEASES, 2001, 7 (02) :178-182
[6]   Intrapulmonary pharmacokinetics of linezolid [J].
Conte, JE ;
Golden, JA ;
Kipps, J ;
Zurlinden, E .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2002, 46 (05) :1475-1480
[7]   Comparison of mortality associated with methicillin-resistant and methicillin-susceptible Staphylococcus aureus bacteremia:: A meta-analysis [J].
Cosgrove, SE ;
Sakoulas, G ;
Perencevich, EN ;
Schwaber, MJ ;
Karchmer, AW ;
Carmeli, Y .
CLINICAL INFECTIOUS DISEASES, 2003, 36 (01) :53-59
[8]  
Cruciani M, 1996, J ANTIMICROB CHEMOTH, V38, P865
[9]   Methicillin-resistant Staphylococcus aureus:: clinical manifestations and antimicrobial therapy [J].
Cunha, BA .
CLINICAL MICROBIOLOGY AND INFECTION, 2005, 11 :33-42
[10]   Survey of infections due to Staphylococcus species:: Frequency of occurrence and antimicrobial susceptibility of isolates collected in the United States, Canada, Latin America, Europe, and the Western Pacific region for the SENTRY Antimicrobial Surveillance Program, 1997-1999 [J].
Diekema, DJ ;
Pfaller, MA ;
Schmitz, FJ ;
Smayevsky, J ;
Bell, J ;
Jones, RN ;
Beach, M .
CLINICAL INFECTIOUS DISEASES, 2001, 32 :S114-S132