Tying rings for sex

被引：37

作者：

Kalkum, M

Eisenbrandt, R

Lurz, R

Lanka, E

机构：

[1] Rockefeller Univ, Dept Mass Spectrometry & Gaseous Ion Chem, New York, NY 10021 USA

[2] Max Planck Inst Mol Genet, D-14195 Berlin, Germany

[3] Biochem GmbH, A-6250 Kundl, Austria

来源：

TRENDS IN MICROBIOLOGY | 2002年 / 10卷 / 08期

关键词：

D O I：

10.1016/S0966-842X(02)02399-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The primary component of the sex pilus encoded by IncP (RP4) and Ti plasmids has been identified as a circular pilin protein with a peptide bond between the amino and carboxyl terminus. Here, we review the key experiments that led to this discovery, and the present mechanistic model for pilin-precursor processing and the cyclization reaction. In addition, we discuss the implications for horizontal gene transfer in bacterial conjugation.

引用

收藏

页码：382 / 387

页数：6

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