Visual perception and working memory in schizotypal personality disorder

被引:50
作者
Farmer, CM
O'Donnell, BF
Niznikiewicz, MA
Voglmaier, MM
McCarley, RW
Shenton, ME
机构
[1] Indiana Univ, Dept Psychol, Bloomington, IN 47405 USA
[2] Harvard Univ, Sch Med, Dept Psychiat, Brockton, MA 02401 USA
[3] Brockton W Roxbury Vet Affairs Med Ctr, Brockton, MA 02401 USA
关键词
D O I
10.1176/appi.ajp.157.5.781
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Objective: Patients affected by schizophrenia show deficits in both visual perception and working memory. The authors tested early-stage vision and working memory in subjects with schizotypal personality disorder, which has been biologically associated with schizophrenia. Method: Eleven subjects who met DSM-III-R criteria for schizotypal personality disorder and 12 normal comparison subjects were evaluated. Performance thresholds were obtained for tests of visual discrimination and working memory. Both form and trajectory processing were evaluated for each task. Results: Subjects with schizotypal personality disorder showed intact discrimination of form and trajectory but were impaired on working memory tasks. Conclusions: These data suggest that subjects with schizotypal personality disorder, unlike patients affected by schizophrenia, have relatively intact visual perception. Subjects with schizotypal personality disorder do show specific deficits on tasks of comparable difficulty when working memory demands are imposed. Schizotypal personality disorder may be associated with a more specific visual processing deficit than schizophrenia, possibly reflecting disruption of frontal lobe systems subserving visual working memory operations.
引用
收藏
页码:781 / 786
页数:6
相关论文
共 41 条
[1]   A unitary model of schizophrenia -: Bleuler's "fragmented phrene" as schizencephaly [J].
Andreasen, NC .
ARCHIVES OF GENERAL PSYCHIATRY, 1999, 56 (09) :781-787
[2]   The Freiburg Visual Acuity test - Automatic measurement of visual acuity [J].
Bach, M .
OPTOMETRY AND VISION SCIENCE, 1996, 73 (01) :49-53
[3]  
BARON M, 1985, AM J PSYCHIAT, V142, P447
[4]   IMPAIRED SPEED OF INFORMATION-PROCESSING IN NON-MEDICATED SCHIZOTYPAL PATIENTS [J].
BRAFF, DL .
SCHIZOPHRENIA BULLETIN, 1981, 7 (03) :499-508
[5]   Transient versus sustained visual channels in the visual backward masking deficits of schizophrenia patients [J].
Cadenhead, KS ;
Serper, Y ;
Braff, DL .
BIOLOGICAL PSYCHIATRY, 1998, 43 (02) :132-138
[6]   The relationship of information-processing deficits and clinical symptoms in schizotypal personality disorder [J].
Cadenhead, KS ;
Perry, W ;
Braff, DL .
BIOLOGICAL PSYCHIATRY, 1996, 40 (09) :853-858
[7]   Spatial working memory deficits and their relationship to negative symptoms in unmedicated schizophrenia patients [J].
Carter, C ;
Robertson, L ;
Nordahl, T ;
Chaderjian, M ;
Kraft, L ;
OShoraCelaya, L .
BIOLOGICAL PSYCHIATRY, 1996, 40 (09) :930-932
[8]   MEASUREMENT OF DIFFERENTIAL DEFICIT [J].
CHAPMAN, LJ ;
CHAPMAN, JP .
JOURNAL OF PSYCHIATRIC RESEARCH, 1978, 14 (1-4) :303-311
[9]   Motion perception in schizophrenia [J].
Chen, Y ;
Palafox, GP ;
Nakayama, K ;
Levy, DL ;
Matthysse, S ;
Holzman, PS .
ARCHIVES OF GENERAL PSYCHIATRY, 1999, 56 (02) :149-154
[10]  
GoldmanRakic PS, 1997, SCHIZOPHRENIA BULL, V23, P437, DOI 10.1093/schbul/23.3.437